Human Gene KATNBL1 (uc001zhp.3) Description and Page Index
  Description: Homo sapiens katanin p80 subunit B-like 1 (KATNBL1), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr15:34,432,875-34,502,297 Size: 69,423 Total Exon Count: 10 Strand: -
Coding Region
   Position: hg19 chr15:34,434,540-34,455,877 Size: 21,338 Coding Exon Count: 9 

Page IndexSequence and LinksUniProtKB CommentsCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr15:34,432,875-34,502,297)mRNA (may differ from genome)Protein (304 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCHPRDLynxMGI
neXtProtOMIMPubMedStanford SOURCETreefamUniProtKB
Wikipedia

-  Comments and Description Text from UniProtKB
  ID: KTBL1_HUMAN
DESCRIPTION: RecName: Full=KATNB1-like protein 1; AltName: Full=Katanin p80 subunit B-like 1;
SEQUENCE CAUTION: Sequence=BAB15394.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 7.57 RPKM in Esophagus - Mucosa
Total median expression: 212.69 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -81.70160-0.511 Picture PostScript Text
3' UTR -381.251665-0.229 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF13925 - con80 domain of Katanin

ModBase Predicted Comparative 3D Structure on Q9H079
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
 Protein SequenceProtein Sequence   
 AlignmentAlignment   

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding

Biological Process:
GO:0051495 positive regulation of cytoskeleton organization

Cellular Component:
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0097431 mitotic spindle pole


-  Descriptions from all associated GenBank mRNAs
  KJ894729 - Synthetic construct Homo sapiens clone ccsbBroadEn_04123 C15orf29 gene, encodes complete protein.
AL136908 - Homo sapiens mRNA; cDNA DKFZp434K229 (from clone DKFZp434K229); complete cds.
AL833631 - Homo sapiens mRNA; cDNA DKFZp686D0879 (from clone DKFZp686D0879).
BC026234 - Homo sapiens chromosome 15 open reading frame 29, mRNA (cDNA clone MGC:22175 IMAGE:4693115), complete cds.
BC111000 - Homo sapiens chromosome 15 open reading frame 29, mRNA (cDNA clone MGC:117356 IMAGE:5751934), complete cds.
AK293021 - Homo sapiens cDNA FLJ76488 complete cds.
AK311338 - Homo sapiens cDNA, FLJ18380.
AK293695 - Homo sapiens cDNA FLJ57951 complete cds.
AK297904 - Homo sapiens cDNA FLJ57751 complete cds.
LF348566 - JP 2014500723-A/156069: Polycomb-Associated Non-Coding RNAs.
JD511130 - Sequence 492154 from Patent EP1572962.
JD239511 - Sequence 220535 from Patent EP1572962.
JD427280 - Sequence 408304 from Patent EP1572962.
JD261656 - Sequence 242680 from Patent EP1572962.
JD164235 - Sequence 145259 from Patent EP1572962.
JD510470 - Sequence 491494 from Patent EP1572962.
AK026210 - Homo sapiens cDNA: FLJ22557 fis, clone HSI01483.
JD339389 - Sequence 320413 from Patent EP1572962.
JD184259 - Sequence 165283 from Patent EP1572962.
JD311538 - Sequence 292562 from Patent EP1572962.
JD302315 - Sequence 283339 from Patent EP1572962.
LF348565 - JP 2014500723-A/156068: Polycomb-Associated Non-Coding RNAs.
LF348564 - JP 2014500723-A/156067: Polycomb-Associated Non-Coding RNAs.
JD553681 - Sequence 534705 from Patent EP1572962.
AM393535 - Synthetic construct Homo sapiens clone IMAGE:100001644 for hypothetical protein (C15orf29 gene).
CU693166 - Synthetic construct Homo sapiens gateway clone IMAGE:100022214 5' read C15orf29 mRNA.
AK021466 - Homo sapiens cDNA FLJ11404 fis, clone HEMBA1000749.
LF348563 - JP 2014500723-A/156066: Polycomb-Associated Non-Coding RNAs.
LF348562 - JP 2014500723-A/156065: Polycomb-Associated Non-Coding RNAs.
BC047748 - Homo sapiens chromosome 15 open reading frame 29, mRNA (cDNA clone IMAGE:6201555), partial cds.
JD284596 - Sequence 265620 from Patent EP1572962.
MA584143 - JP 2018138019-A/156069: Polycomb-Associated Non-Coding RNAs.
MA584142 - JP 2018138019-A/156068: Polycomb-Associated Non-Coding RNAs.
MA584141 - JP 2018138019-A/156067: Polycomb-Associated Non-Coding RNAs.
MA584140 - JP 2018138019-A/156066: Polycomb-Associated Non-Coding RNAs.
MA584139 - JP 2018138019-A/156065: Polycomb-Associated Non-Coding RNAs.
LF205826 - JP 2014500723-A/13329: Polycomb-Associated Non-Coding RNAs.
BC037234 - Homo sapiens chromosome 15 open reading frame 29, mRNA (cDNA clone IMAGE:5197947), partial cds.
MA441403 - JP 2018138019-A/13329: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: A8KAF6, C15orf29, KTBL1_HUMAN, NM_024713, NP_078989, Q2TAC0, Q9H079, Q9H670
UCSC ID: uc001zhp.3
RefSeq Accession: NM_024713
Protein: Q9H079 (aka KTBL1_HUMAN)
CCDS: CCDS10034.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_024713.2
exon count: 10CDS single in 3' UTR: no RNA size: 2750
ORF size: 915CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1960.00frame shift in genome: no % Coverage: 99.64
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.