Human Gene C7orf55-LUC7L2 (uc011kqt.3) Description and Page Index
  Description: Homo sapiens C7orf55-LUC7L2 readthrough (C7orf55-LUC7L2), mRNA.
RefSeq Summary (NM_001244584): This locus represents naturally occurring readthrough transcription between the neighboring C7orf55 (chromosome 7 open reading frame 55) and LUC7L2 (LUC7-like 2) genes on chromosome 7. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Jul 2012]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.197131.1, SRR1803615.75846.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## readthrough transcript :: includes exons from GeneID 51631, 154791 ##RefSeq-Attributes-END##
Transcript (Including UTRs)
   Position: hg19 chr7:139,025,878-139,108,203 Size: 82,326 Total Exon Count: 11 Strand: +
Coding Region
   Position: hg19 chr7:139,026,131-139,107,086 Size: 80,956 Coding Exon Count: 11 

Page IndexSequence and LinksGene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:139,025,878-139,108,203)mRNA (may differ from genome)Protein (458 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaBioGPS
CGAPEnsemblEntrez GeneExonPrimerGeneCardsH-INV
HGNCLynxMGIPubMedStanford SOURCEUniProtKB

+  Common Gene Haplotype Alleles
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-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 12.65 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 332.74 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -97.40253-0.385 Picture PostScript Text
3' UTR -283.961117-0.254 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR004882 - LUC7-rel

Pfam Domains:
PF03194 - LUC7 N_terminus

ModBase Predicted Comparative 3D Structure on B7Z4Q3
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
 Protein Sequence    
 Alignment    

-  Descriptions from all associated GenBank mRNAs
  AK298166 - Homo sapiens cDNA FLJ55994 complete cds, highly similar to RNA-binding protein Luc7-like 2.
AK297642 - Homo sapiens cDNA FLJ55988 complete cds, highly similar to RNA-binding protein Luc7-like 2.
LF384098 - JP 2014500723-A/191601: Polycomb-Associated Non-Coding RNAs.
AK093864 - Homo sapiens cDNA FLJ36545 fis, clone TRACH2006670, highly similar to RNA-binding protein Luc7-like 2.
AK001519 - Homo sapiens cDNA FLJ10657 fis, clone NT2RP2006043, weakly similar to SPLICING FACTOR, ARGININE/SERINE-RICH 4.
BC042625 - Homo sapiens LUC7-like 2 (S. cerevisiae), mRNA (cDNA clone MGC:35315 IMAGE:5178074), complete cds.
BC050708 - Homo sapiens LUC7-like 2 (S. cerevisiae), mRNA (cDNA clone MGC:60313 IMAGE:6500791), complete cds.
BC017163 - Homo sapiens LUC7-like 2 (S. cerevisiae), mRNA (cDNA clone MGC:8819 IMAGE:3920377), complete cds.
AK001476 - Homo sapiens cDNA FLJ10614 fis, clone NT2RP2005436, weakly similar to SPLICING FACTOR, ARGININE/SERINE-RICH 4.
BC056886 - Homo sapiens LUC7-like 2 (S. cerevisiae), mRNA (cDNA clone MGC:65020 IMAGE:6147116), complete cds.
AK022895 - Homo sapiens cDNA FLJ12833 fis, clone NT2RP2003157, weakly similar to SPLICING FACTOR, ARGININE/SERINE-RICH 4.
AB528652 - Synthetic construct DNA, clone: pF1KB6550, Homo sapiens LUC7L2 gene for LUC7-like protein 2, without stop codon, in Flexi system.
EU832106 - Synthetic construct Homo sapiens clone HAIB:100067135; DKFZo008B0825 LUC7-like 2 (S. cerevisiae) protein (LUC7L2) gene, encodes complete protein.
EU832200 - Synthetic construct Homo sapiens clone HAIB:100067229; DKFZo004B0826 LUC7-like 2 (S. cerevisiae) protein (LUC7L2) gene, encodes complete protein.
CU677843 - Synthetic construct Homo sapiens gateway clone IMAGE:100017165 5' read LUC7L2 mRNA.
HQ448242 - Synthetic construct Homo sapiens clone IMAGE:100071643; CCSB000258_01 LUC7-like 2 (S. cerevisiae) (LUC7L2) gene, encodes complete protein.
KJ893955 - Synthetic construct Homo sapiens clone ccsbBroadEn_03349 LUC7L2 gene, encodes complete protein.
AF151832 - Homo sapiens CGI-74 protein mRNA, complete cds.
AF151817 - Homo sapiens CGI-59 protein mRNA, complete cds.
AK095839 - Homo sapiens cDNA FLJ38520 fis, clone HCHON2000781, weakly similar to Cisplatin resistance-associated overexpressed protein.
AK092044 - Homo sapiens cDNA FLJ34725 fis, clone MESAN2005958, highly similar to RNA-binding protein Luc7-like 2.
MA619675 - JP 2018138019-A/191601: Polycomb-Associated Non-Coding RNAs.
LF384096 - JP 2014500723-A/191599: Polycomb-Associated Non-Coding RNAs.
JD080489 - Sequence 61513 from Patent EP1572962.
AF161386 - Homo sapiens HSPC268 mRNA, partial cds.
BC008467 - Homo sapiens chromosome 7 open reading frame 55, mRNA (cDNA clone MGC:14732 IMAGE:4276817), complete cds.
AK093018 - Homo sapiens cDNA FLJ35699 fis, clone SPLEN2019956.
JD464958 - Sequence 445982 from Patent EP1572962.
AB528093 - Synthetic construct DNA, clone: pF1KE0163, Homo sapiens FMC1 gene for chromosome 7 open reading frame 55, without stop codon, in Flexi system.
AM393147 - Synthetic construct Homo sapiens clone IMAGE:100002119 for hypothetical protein (HSPC268 gene).
DQ893149 - Synthetic construct clone IMAGE:100005779; FLH194358.01X; RZPDo839A0680D hypothetical protein HSPC268 (HSPC268) gene, encodes complete protein.
DQ896444 - Synthetic construct Homo sapiens clone IMAGE:100010904; FLH194354.01L; RZPDo839A0670D hypothetical protein HSPC268 (HSPC268) gene, encodes complete protein.
KJ905015 - Synthetic construct Homo sapiens clone ccsbBroadEn_14409 C7orf55-like gene, encodes complete protein.
MA619673 - JP 2018138019-A/191599: Polycomb-Associated Non-Coding RNAs.
AK094081 - Homo sapiens cDNA FLJ36762 fis, clone UTERU2018955, highly similar to RNA-binding protein Luc7-like 2.
BC041001 - Homo sapiens LUC7-like 2 (S. cerevisiae), mRNA (cDNA clone IMAGE:5273893).
JD508848 - Sequence 489872 from Patent EP1572962.
JD263959 - Sequence 244983 from Patent EP1572962.
JD382755 - Sequence 363779 from Patent EP1572962.
JD154855 - Sequence 135879 from Patent EP1572962.
JD137171 - Sequence 118195 from Patent EP1572962.
JD058839 - Sequence 39863 from Patent EP1572962.
JD521116 - Sequence 502140 from Patent EP1572962.
JD379297 - Sequence 360321 from Patent EP1572962.
JD261339 - Sequence 242363 from Patent EP1572962.
JD525082 - Sequence 506106 from Patent EP1572962.
JD248240 - Sequence 229264 from Patent EP1572962.
JD359754 - Sequence 340778 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B7Z4Q3, B7Z4Q3_HUMAN, LUC7L2, NM_001244584, NP_001231513, uc011kqt.2
UCSC ID: uc011kqt.3
RefSeq Accession: NM_001244584
Protein: B7Z4Q3 CCDS: CCDS59084.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001244584.2
exon count: 11CDS single in 3' UTR: no RNA size: 2747
ORF size: 1377CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2954.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.