Description: Homo sapiens zinc finger with KRAB and SCAN domains 1 (ZKSCAN1), mRNA. RefSeq Summary (NM_003439): This gene encodes a member of the Kruppel C2H2-type zinc-finger family of proteins. This encoded protein may function as a transcription factor that regulates the expression of GABA type-A receptors in the brain. Transcripts from this gene have been shown to form stable and abundant circular RNAs. Elevated expression of this gene has been observed in gastric cancer and the encoded protein may stimulate migration and invasion of human gastric cancer cells. [provided by RefSeq, Oct 2016]. Transcript (Including UTRs) Position: hg19 chr7:99,613,219-99,622,583 Size: 9,365 Total Exon Count: 3 Strand: + Coding Region Position: hg19 chr7:99,621,133-99,621,953 Size: 821 Coding Exon Count: 2
ID:C9JRM9_HUMAN DESCRIPTION: SubName: Full=Zinc finger protein with KRAB and SCAN domains 1; Flags: Fragment; SIMILARITY: Contains 1 SCAN box domain. CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on C9JRM9
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.