Human Gene ZNF763 (uc002msv.3)
  Description: Homo sapiens zinc finger protein 763 (ZNF763), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr19:12,075,869-12,091,198 Size: 15,330 Total Exon Count: 4 Strand: +
Coding Region
   Position: hg19 chr19:12,076,024-12,089,924 Size: 13,901 Coding Exon Count: 4 

Page IndexSequence and LinksPrimersMalaCardsGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr19:12,075,869-12,091,198)mRNA (may differ from genome)Protein (397 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCHPRDLynxMalacards
MGIPubMedTreefamUniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: ZNF763
Diseases sorted by gene-association score: split hand-foot malformation 1 (2)

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 1.11 RPKM in Bladder
Total median expression: 25.41 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -52.20155-0.337 Picture PostScript Text
3' UTR -365.311274-0.287 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF00096 - Zinc finger, C2H2 type
PF01352 - KRAB box
PF13894 - C2H2-type zinc finger
PF13912 - C2H2-type zinc finger

SCOP Domains:
48695 - Multiheme cytochromes
109640 - KRAB domain (Kruppel-associated box, Pfam 01352)
57667 - C2H2 and C2HC zinc fingers

ModBase Predicted Comparative 3D Structure on Q0D2J5-2
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AK299182 - Homo sapiens cDNA FLJ58611 complete cds, highly similar to Homo sapiens zinc finger protein 440 like (ZNF440L), mRNA.
AK299224 - Homo sapiens cDNA FLJ58613 complete cds, highly similar to Homo sapiens zinc finger protein 440 like (ZNF440L), mRNA.
AK092240 - Homo sapiens cDNA FLJ34921 fis, clone NT2RP7002978, moderately similar to Zinc finger protein 440.
AX747424 - Sequence 949 from Patent EP1308459.
BC105711 - Homo sapiens zinc finger protein 763, mRNA (cDNA clone MGC:125563 IMAGE:40024621), complete cds.
BC105712 - Homo sapiens zinc finger protein 763, mRNA (cDNA clone MGC:125561 IMAGE:40024618), complete cds.
BC105713 - Homo sapiens zinc finger protein 763, mRNA (cDNA clone MGC:125560 IMAGE:40024617), complete cds.
AB528905 - Synthetic construct DNA, clone: pF1KE0674, Homo sapiens ZNF763 gene for zinc finger protein 763, without stop codon, in Flexi system.
JD326367 - Sequence 307391 from Patent EP1572962.
JD365462 - Sequence 346486 from Patent EP1572962.
DQ572200 - Homo sapiens piRNA piR-40312, complete sequence.
JD503887 - Sequence 484911 from Patent EP1572962.
JD486559 - Sequence 467583 from Patent EP1572962.
JD202963 - Sequence 183987 from Patent EP1572962.
JD246010 - Sequence 227034 from Patent EP1572962.
JD369433 - Sequence 350457 from Patent EP1572962.
JD363493 - Sequence 344517 from Patent EP1572962.
JD173964 - Sequence 154988 from Patent EP1572962.
JD379462 - Sequence 360486 from Patent EP1572962.
JD533732 - Sequence 514756 from Patent EP1572962.
JD043386 - Sequence 24410 from Patent EP1572962.
JD541607 - Sequence 522631 from Patent EP1572962.
JD155105 - Sequence 136129 from Patent EP1572962.
JD182446 - Sequence 163470 from Patent EP1572962.
JD548159 - Sequence 529183 from Patent EP1572962.
JD143526 - Sequence 124550 from Patent EP1572962.
JD144586 - Sequence 125610 from Patent EP1572962.
JD400290 - Sequence 381314 from Patent EP1572962.
JD424462 - Sequence 405486 from Patent EP1572962.
JD238572 - Sequence 219596 from Patent EP1572962.
JD508961 - Sequence 489985 from Patent EP1572962.
JD294258 - Sequence 275282 from Patent EP1572962.
JD277317 - Sequence 258341 from Patent EP1572962.
JD472672 - Sequence 453696 from Patent EP1572962.
JD282073 - Sequence 263097 from Patent EP1572962.
JD270214 - Sequence 251238 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: NM_001012753, NP_001012771, Q0D2J5-2
UCSC ID: uc002msv.3
RefSeq Accession: NM_001012753
Protein: Q0D2J5-2, splice isoform of Q0D2J5 CCDS: CCDS45982.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001012753.1
exon count: 4CDS single in 3' UTR: no RNA size: 2639
ORF size: 1194CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2357.00frame shift in genome: no % Coverage: 99.39
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.