Human Gene TMEM222 (uc001bnr.4)
Description: Homo sapiens transmembrane protein 222 (TMEM222), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr1:27,648,636-27,662,891 Size: 14,256 Total Exon Count: 6 Strand: +
Coding Region
Position: hg19 chr1:27,648,689-27,661,957 Size: 13,269 Coding Exon Count: 6
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: TM222_HUMAN
DESCRIPTION: RecName: Full=Transmembrane protein 222;
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).SEQUENCE CAUTION: Sequence=CAB66618.1; Type=Erroneous initiation;
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR008496 - DUF778
Pfam Domains: PF05608 - Protein of unknown function (DUF778)
ModBase Predicted Comparative 3D Structure on Q9H0R3
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK313110 - Homo sapiens cDNA, FLJ93595.AK303821 - Homo sapiens cDNA FLJ56305 complete cds.AL136683 - Homo sapiens mRNA; cDNA DKFZp564D0478 (from clone DKFZp564D0478).BC011579 - Homo sapiens transmembrane protein 222, mRNA (cDNA clone IMAGE:4548544), partial cds.BC090039 - Homo sapiens transmembrane protein 222, mRNA (cDNA clone MGC:111002 IMAGE:6181849), complete cds.EU831513 - Synthetic construct Homo sapiens clone HAIB:100066542; DKFZo004B0718 chromosome 1 open reading frame 160 protein (C1orf160) gene, encodes complete protein.KJ904908 - Synthetic construct Homo sapiens clone ccsbBroadEn_14302 TMEM222 gene, encodes complete protein.EU831420 - Synthetic construct Homo sapiens clone HAIB:100066449; DKFZo008B0717 chromosome 1 open reading frame 160 protein (C1orf160) gene, encodes complete protein.AF251699 - Homo sapiens hypothetical protein SB71 mRNA, complete cds.AK222642 - Homo sapiens mRNA for hypothetical protein DKFZp564D0478 variant, clone: CBL02969.AK307077 - Homo sapiens cDNA, FLJ97025.JD271282 - Sequence 252306 from Patent EP1572962.AK123218 - Homo sapiens cDNA FLJ41224 fis, clone BRAMY2030098.AK095889 - Homo sapiens cDNA FLJ38570 fis, clone HCHON2006722.JD396340 - Sequence 377364 from Patent EP1572962.JD210155 - Sequence 191179 from Patent EP1572962.JD114748 - Sequence 95772 from Patent EP1572962.JD102628 - Sequence 83652 from Patent EP1572962.JD424797 - Sequence 405821 from Patent EP1572962.JD338840 - Sequence 319864 from Patent EP1572962.JD189300 - Sequence 170324 from Patent EP1572962.JD173179 - Sequence 154203 from Patent EP1572962.JD066153 - Sequence 47177 from Patent EP1572962.JD432795 - Sequence 413819 from Patent EP1572962.JD198676 - Sequence 179700 from Patent EP1572962.JD109771 - Sequence 90795 from Patent EP1572962.JD507122 - Sequence 488146 from Patent EP1572962.JD104444 - Sequence 85468 from Patent EP1572962.JD478836 - Sequence 459860 from Patent EP1572962.JD222808 - Sequence 203832 from Patent EP1572962.JD451044 - Sequence 432068 from Patent EP1572962.JD371499 - Sequence 352523 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: C1orf160, D3DPL6, NM_032125, NP_115501, Q53HD8, Q5FVE9, Q9H0R3, TM222_HUMANUCSC ID: uc001bnr.4RefSeq Accession: NM_032125
Protein: Q9H0R3
(aka TM222_HUMAN)
CCDS: CCDS297.2
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_032125.2
exon count:
6 CDS single in 3' UTR:
no
RNA size:
1629
ORF size:
627 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1182.00 frame shift in genome:
no
% Coverage:
99.08
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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