Human Gene RUSC1-AS1 (uc001fki.3)
  Description: Homo sapiens RUSC1 antisense RNA 1 (RUSC1-AS1), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr1:155,290,251-155,293,938 Size: 3,688 Total Exon Count: 2 Strand: -
Coding Region
   Position: hg19 chr1:155,290,569-155,291,279 Size: 711 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr1:155,290,251-155,293,938)mRNA (may differ from genome)Protein (236 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblExonPrimerGeneCardsGeneNetworkHGNCHPRD
LynxMGIneXtProtPubMedUniProtKB

-  Comments and Description Text from UniProtKB
  ID: RUAS1_HUMAN
DESCRIPTION: RecName: Full=Putative uncharacterized protein RUSC1-AS1; AltName: Full=RUSC1 antisense RNA 1; AltName: Full=RUSC1 antisense gene protein 1;
CAUTION: Product of a dubious CDS prediction.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 41.00 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 712.06 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -94.90277-0.343 Picture PostScript Text
3' UTR -103.04318-0.324 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q66K80
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding


-  Descriptions from all associated GenBank mRNAs
  AK093295 - Homo sapiens cDNA FLJ35976 fis, clone TESTI2013427.
AX748038 - Sequence 1563 from Patent EP1308459.
BC131614 - Homo sapiens chromosome 1 open reading frame 104, mRNA (cDNA clone MGC:149516 IMAGE:40115930), complete cds.
KJ904140 - Synthetic construct Homo sapiens clone ccsbBroadEn_13534 RUSC1-AS1 gene, encodes complete protein.
BC062571 - Homo sapiens chromosome 1 open reading frame 104, mRNA (cDNA clone MGC:70363 IMAGE:5183308), complete cds.
BC080538 - Homo sapiens chromosome 1 open reading frame 104, mRNA (cDNA clone MGC:99462 IMAGE:5018492), complete cds.
LF211904 - JP 2014500723-A/19407: Polycomb-Associated Non-Coding RNAs.
JD020762 - Sequence 1786 from Patent EP1572962.
JD030709 - Sequence 11733 from Patent EP1572962.
KJ900573 - Synthetic construct Homo sapiens clone ccsbBroadEn_09967 RUSC1-AS1 gene, encodes complete protein.
MA447481 - JP 2018138019-A/19407: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: C1orf104, NM_001039517, NP_001034606, Q66K80, Q8NA07, RUAS1_HUMAN
UCSC ID: uc001fki.3
RefSeq Accession: NM_001039517
Protein: Q66K80 (aka RUAS1_HUMAN)

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001039517.1
exon count: 2CDS single in 3' UTR: no RNA size: 1326
ORF size: 711CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1530.00frame shift in genome: no % Coverage: 98.49
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.