Description: Homo sapiens SHC SH2-domain binding protein 1-like (SHCBP1L), mRNA. RefSeq Summary (NM_030933): This gene encodes a Src homology 2 domain-binding protein 1-like protein. The encoded protein interacts with heat shock 70 kDa protein 2 and may be involved in maintaining spindle integrity during meiosis. This gene is located in region of chromoso0me 1 encompassing a prostate cancer susceptibility locus. [provided by RefSeq, Sep 2016]. Transcript (Including UTRs) Position: hg19 chr1:182,869,000-182,922,553 Size: 53,554 Total Exon Count: 11 Strand: - Coding Region Position: hg19 chr1:182,869,118-182,921,119 Size: 52,002 Coding Exon Count: 10
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF05048 - Periplasmic copper-binding protein (NosD) PF13229 - Right handed beta helix region
ModBase Predicted Comparative 3D Structure on Q9BZQ2-2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.