Human Gene TASOR2 (uc001iik.3)
  Description: Homo sapiens family with sequence similarity 208, member B (TASOR2), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr10:5,772,735-5,805,703 Size: 32,969 Total Exon Count: 8 Strand: +
Coding Region
   Position: hg19 chr10:5,788,853-5,804,995 Size: 16,143 Coding Exon Count: 7 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr10:5,772,735-5,805,703)mRNA (may differ from genome)Protein (1274 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblExonPrimerGeneCardsGeneNetworkH-INV
HPRDLynxMGIneXtProtPubMedTreefam
UniProtKB

-  Comments and Description Text from UniProtKB
  ID: F208B_HUMAN
DESCRIPTION: RecName: Full=Protein FAM208B;
SIMILARITY: Belongs to the FAM208 family.
SEQUENCE CAUTION: Sequence=BAA91115.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB14336.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAB14993.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=BAC87251.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 12.76 RPKM in Testis
Total median expression: 321.02 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -70.70280-0.252 Picture PostScript Text
3' UTR -142.70708-0.202 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR022168 - DUF3699
IPR022188 - DUF3715

ModBase Predicted Comparative 3D Structure on Q5VWN6
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserNo orthologGenome BrowserNo ortholog
Gene Details   Gene Details 
Gene Sorter   Gene Sorter 
  Ensembl WormBase 
  Protein Sequence Protein Sequence 
  Alignment Alignment 

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding

Cellular Component:
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol


-  Descriptions from all associated GenBank mRNAs
  CR936780 - Homo sapiens mRNA; cDNA DKFZp781E1986 (from clone DKFZp781E1986).
AK309877 - Homo sapiens cDNA, FLJ99918.
BC166686 - Synthetic construct Homo sapiens clone IMAGE:100066412, MGC:195549 chromosome 10 open reading frame 18 (C10orf18) mRNA, encodes complete protein.
BX649177 - Homo sapiens mRNA; cDNA DKFZp779E1157 (from clone DKFZp779E1157).
AK128211 - Homo sapiens cDNA FLJ46343 fis, clone TESTI4046962.
AB095927 - Homo sapiens mRNA for KIAA2006 protein.
BC016688 - Homo sapiens chromosome 10 open reading frame 18, mRNA (cDNA clone IMAGE:4342902), partial cds.
AK128051 - Homo sapiens cDNA FLJ46171 fis, clone TESTI4003565.
AL832762 - Homo sapiens mRNA; cDNA DKFZp686G2327 (from clone DKFZp686G2327).
AK128055 - Homo sapiens cDNA FLJ46175 fis, clone TESTI4003703, weakly similar to Homo sapiens retinoblastoma-associated protein (RAP140).
AK128151 - Homo sapiens cDNA FLJ46274 fis, clone TESTI4029297.
AK091392 - Homo sapiens cDNA FLJ34073 fis, clone FCBBF3002658.
AX746956 - Sequence 481 from Patent EP1308459.
BC071976 - Homo sapiens chromosome 10 open reading frame 18, mRNA (cDNA clone IMAGE:3939979), partial cds.
BC001759 - Homo sapiens chromosome 10 open reading frame 18, mRNA (cDNA clone IMAGE:3354582), partial cds.
AK225352 - Homo sapiens mRNA for chromosome 10 open reading frame 18 variant, clone: HEP16677.
AK000367 - Homo sapiens cDNA FLJ20360 fis, clone HEP16677.
JD043088 - Sequence 24112 from Patent EP1572962.
CU674870 - Synthetic construct Homo sapiens gateway clone IMAGE:100020052 5' read C10orf18 mRNA.
KJ904782 - Synthetic construct Homo sapiens clone ccsbBroadEn_14176 FAM208B gene, encodes complete protein.
AK022966 - Homo sapiens cDNA FLJ12904 fis, clone NT2RP2004365.
AK027014 - Homo sapiens cDNA: FLJ23361 fis, clone HEP15231.
AK024762 - Homo sapiens cDNA: FLJ21109 fis, clone CAS05324.
BC110339 - Homo sapiens chromosome 10 open reading frame 18, mRNA (cDNA clone IMAGE:5756954), partial cds.
BC020304 - Homo sapiens chromosome 10 open reading frame 18, mRNA (cDNA clone IMAGE:4149739), with apparent retained intron.
AK095469 - Homo sapiens cDNA FLJ38150 fis, clone D9OST2004073.
JD505005 - Sequence 486029 from Patent EP1572962.
JD305791 - Sequence 286815 from Patent EP1572962.
JD404014 - Sequence 385038 from Patent EP1572962.
JD301723 - Sequence 282747 from Patent EP1572962.
JD363505 - Sequence 344529 from Patent EP1572962.
JD234984 - Sequence 216008 from Patent EP1572962.
JD499299 - Sequence 480323 from Patent EP1572962.
JD093961 - Sequence 74985 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AB095927, C10orf18, F208B_HUMAN, FAM208B, KIAA2006, Q2YD91, Q5VWN5, Q5VWN6, Q6ZRQ8, Q8IVG4, Q9BUZ7, Q9H5J9, Q9H7A4, Q9H996, Q9NXA1
UCSC ID: uc001iik.3
RefSeq Accession: NM_017782
Protein: Q5VWN6 (aka F208B_HUMAN)

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: AB095927.1
exon count: 8CDS single in 3' UTR: no RNA size: 4810
ORF size: 3825CDS single in intron: no Alignment % ID: 99.96
txCdsPredict score: 7557.00frame shift in genome: no % Coverage: 99.98
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.