Human Gene ZFAND4 (uc001jcm.4)
Description: Homo sapiens zinc finger, AN1-type domain 4 (ZFAND4), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr10:46,111,039-46,168,251 Size: 57,213 Total Exon Count: 10 Strand: -
Coding Region
Position: hg19 chr10:46,111,884-46,159,173 Size: 47,290 Coding Exon Count: 9
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: ZFAN4_HUMAN
DESCRIPTION: RecName: Full=AN1-type zinc finger protein 4; AltName: Full=AN1-type zinc finger and ubiquitin domain-containing protein-like 1;
SIMILARITY: Contains 1 AN1-type zinc finger.SIMILARITY: Contains 1 ubiquitin-like domain.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR000626 - Ubiquitin
IPR019956 - Ubiquitin_subgr
IPR019955 - Ubiquitin_supergroup
IPR000058 - Znf_AN1
Pfam Domains: PF00240 - Ubiquitin family
PF01428 - AN1-like Zinc finger
PF14560 - Ubiquitin-like domain
SCOP Domains: 54236 - Ubiquitin-like
ModBase Predicted Comparative 3D Structure on Q86XD8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
BC045587 - Homo sapiens AN1, ubiquitin-like, homolog (Xenopus laevis), mRNA (cDNA clone MGC:57415 IMAGE:5269483), complete cds.AF311324 - Homo sapiens ubiquitin-like fusion protein mRNA, complete cds.BC036186 - Homo sapiens AN1, ubiquitin-like, homolog (Xenopus laevis), mRNA (cDNA clone IMAGE:5303535), **** WARNING: chimeric clone ****.BC048967 - Homo sapiens AN1, ubiquitin-like, homolog (Xenopus laevis), mRNA (cDNA clone IMAGE:5314527), **** WARNING: chimeric clone ****.AK090704 - Homo sapiens cDNA FLJ33385 fis, clone BRACE2006547, highly similar to Homo sapiens AN1, ubiquitin-like, homolog (Xenopus laevis) (ANUBL1), mRNA.AX746581 - Sequence 106 from Patent EP1308459.BC048968 - Homo sapiens AN1, ubiquitin-like, homolog (Xenopus laevis), mRNA (cDNA clone MGC:57202 IMAGE:5272133), complete cds.AK292469 - Homo sapiens cDNA FLJ78689 complete cds, highly similar to Homo sapiens AN1, ubiquitin-like, homolog (Xenopus laevis), mRNA.AK292420 - Homo sapiens cDNA FLJ75137 complete cds, highly similar to Homo sapiens AN1, ubiquitin-like, homolog (Xenopus laevis), mRNA.AK097504 - Homo sapiens cDNA FLJ40185 fis, clone TESTI2018565, highly similar to Homo sapiens AN1, ubiquitin-like, homolog (Xenopus laevis) (ANUBL1), mRNA.AK314395 - Homo sapiens cDNA, FLJ95171, highly similar to Homo sapiens AN1, ubiquitin-like, homolog (Xenopus laevis) (ANUBL1), mRNA.JF432339 - Synthetic construct Homo sapiens clone IMAGE:100073527 AN1, ubiquitin-like, homolog (Xenopus laevis) (ANUBL1) gene, encodes complete protein.KJ903602 - Synthetic construct Homo sapiens clone ccsbBroadEn_12996 ZFAND4 gene, encodes complete protein.CU690590 - Synthetic construct Homo sapiens gateway clone IMAGE:100021004 5' read ANUBL1 mRNA.BC017591 - Homo sapiens AN1, ubiquitin-like, homolog (Xenopus laevis), mRNA (cDNA clone IMAGE:4828824), with apparent retained intron.JD196962 - Sequence 177986 from Patent EP1572962.JD356943 - Sequence 337967 from Patent EP1572962.JD053265 - Sequence 34289 from Patent EP1572962.JD350111 - Sequence 331135 from Patent EP1572962.JD506373 - Sequence 487397 from Patent EP1572962.JD565001 - Sequence 546025 from Patent EP1572962.JD048061 - Sequence 29085 from Patent EP1572962.JD250749 - Sequence 231773 from Patent EP1572962.AK097924 - Homo sapiens cDNA FLJ40605 fis, clone THYMU2011852, highly similar to Homo sapiens AN1, ubiquitin-like, homolog (Xenopus laevis) (ANUBL1), mRNA.JD462682 - Sequence 443706 from Patent EP1572962.JD383675 - Sequence 364699 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: A8K8V4, ANUBL1, B2RAX2, NM_174890, NP_777550, Q5VVY5, Q86XD8, ZFAN4_HUMANUCSC ID: uc001jcm.4RefSeq Accession: NM_174890
Protein: Q86XD8
(aka ZFAN4_HUMAN)
CCDS: CCDS7214.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_174890.2
exon count:
10 CDS single in 3' UTR:
no
RNA size:
3708
ORF size:
2184 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
4413.00 frame shift in genome:
no
% Coverage:
99.78
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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