Human Gene SLC35G1 (uc001kjf.2)
  Description: Homo sapiens solute carrier family 35, member G1 (SLC35G1), transcript variant 2, mRNA.
RefSeq Summary (NM_153226): This gene encodes a transmembrane protein which is a member of the drug/metabolite transporter protein superfamily. The encoded protein may play a role in the regulation of calcium levels inside the cell. [provided by RefSeq, Sep 2016].
Transcript (Including UTRs)
   Position: hg19 chr10:95,653,730-95,662,491 Size: 8,762 Total Exon Count: 3 Strand: +
Coding Region
   Position: hg19 chr10:95,653,791-95,661,247 Size: 7,457 Coding Exon Count: 3 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr10:95,653,730-95,662,491)mRNA (may differ from genome)Protein (364 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCLynxMGIOMIM
PubMedTreefamUniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 2.67 RPKM in Small Intestine - Terminal Ileum
Total median expression: 42.49 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -29.6061-0.485 Picture PostScript Text
3' UTR -283.881244-0.228 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  Pfam Domains:
PF00892 - EamA-like transporter family

SCOP Domains:
103481 - Multidrug resistance efflux transporter EmrE

ModBase Predicted Comparative 3D Structure on Q2M3R5-2
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC058549 - Homo sapiens cDNA clone IMAGE:6423479, partial cds.
AK091309 - Homo sapiens cDNA FLJ33990 fis, clone DFNES2007299.
AX746907 - Sequence 432 from Patent EP1308459.
BC036382 - Homo sapiens transmembrane protein 20, mRNA (cDNA clone IMAGE:5261668).
BC143283 - Homo sapiens cDNA clone MGC:176803 IMAGE:9051786, complete cds.
BC143284 - Homo sapiens transmembrane protein 20, mRNA (cDNA clone MGC:176804 IMAGE:9051787), complete cds.
BC104814 - Homo sapiens transmembrane protein 20, mRNA (cDNA clone MGC:132474 IMAGE:8143817), complete cds.
BC047102 - Homo sapiens transmembrane protein 20, mRNA (cDNA clone IMAGE:5298765).
KJ895710 - Synthetic construct Homo sapiens clone ccsbBroadEn_05104 SLC35G1 gene, encodes complete protein.
BC041432 - Homo sapiens transmembrane protein 20, mRNA (cDNA clone IMAGE:4525988), partial cds.
JD245101 - Sequence 226125 from Patent EP1572962.
JD503834 - Sequence 484858 from Patent EP1572962.
JD069019 - Sequence 50043 from Patent EP1572962.
JD300536 - Sequence 281560 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: C10orf60, NM_153226, NP_694958, Q2M3R5-2, TMEM20
UCSC ID: uc001kjf.2
RefSeq Accession: NM_153226
Protein: Q2M3R5-2, splice isoform of Q2M3R5 CCDS: CCDS7432.1, CCDS44459.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_153226.2
exon count: 3CDS single in 3' UTR: no RNA size: 2425
ORF size: 1095CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2384.00frame shift in genome: no % Coverage: 98.97
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.