Description: Homo sapiens CWF19-like 1, cell cycle control (S. pombe) (CWF19L1), mRNA. RefSeq Summary (NM_018294): This gene encodes a member of the CWF19 protein family. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia-17 and mild cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]. Transcript (Including UTRs) Position: hg19 chr10:101,992,055-102,027,437 Size: 35,383 Total Exon Count: 13 Strand: - Coding Region Position: hg19 chr10:101,992,984-102,006,656 Size: 13,673 Coding Exon Count: 7
ID:C19L1_HUMAN DESCRIPTION: RecName: Full=CWF19-like protein 1; SIMILARITY: Belongs to the CWF19 family. SEQUENCE CAUTION: Sequence=CAH72402.1; Type=Erroneous gene model prediction;
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Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): CWF19L1 CDC HuGE Published Literature: CWF19L1 Positive Disease Associations: Depressive Disorder, Major Related Studies:
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q69YN2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.