Human Gene ANKRD13D (uc001okc.2)
  Description: Homo sapiens ankyrin repeat domain 13 family, member D (ANKRD13D), transcript variant 2, non-coding RNA.
Transcript (Including UTRs)
   Position: hg19 chr11:67,056,762-67,069,955 Size: 13,194 Total Exon Count: 16 Strand: +
Coding Region
   Position: hg19 chr11:67,057,828-67,069,803 Size: 11,976 Coding Exon Count: 13 

Page IndexSequence and LinksUniProtKB CommentsPrimersGenetic AssociationsCTD
Gene AllelesRNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther Species
GO AnnotationsmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr11:67,056,762-67,069,955)mRNA (may differ from genome)Protein (518 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblExonPrimerGeneCardsH-INV
HGNCHPRDLynxMGIneXtProtPubMed
TreefamUniProtKB

-  Comments and Description Text from UniProtKB
  ID: AN13D_HUMAN
DESCRIPTION: RecName: Full=Ankyrin repeat domain-containing protein 13D;
SIMILARITY: Contains 3 UIM (ubiquitin-interacting motif) repeats.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): ANKRD13D
CDC HuGE Published Literature: ANKRD13D

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 46.74 RPKM in Whole Blood
Total median expression: 747.43 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -277.54568-0.489 Picture PostScript Text
3' UTR -55.50152-0.365 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR021832 - ANKRD13
IPR003903 - Ubiquitin-int_motif

Pfam Domains:
PF02809 - Ubiquitin interaction motif
PF11904 - GPCR-chaperone

ModBase Predicted Comparative 3D Structure on Q6ZTN6
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005737 cytoplasm
GO:0005768 endosome
GO:0005770 late endosome
GO:0005886 plasma membrane
GO:0016020 membrane


-  Descriptions from all associated GenBank mRNAs
  BC110419 - Homo sapiens ankyrin repeat domain 13 family, member D, mRNA (cDNA clone MGC:117203 IMAGE:5210878), complete cds.
AK124721 - Homo sapiens cDNA FLJ42731 fis, clone BRAWH2012162, moderately similar to Homo sapiens KE03 protein.
AK096277 - Homo sapiens cDNA FLJ38958 fis, clone NT2RI2000133, moderately similar to Homo sapiens KE03 protein mRNA.
AK126438 - Homo sapiens cDNA FLJ44474 fis, clone UTERU2031268, weakly similar to Homo sapiens NY-REN-25 antigen.
BC121024 - Homo sapiens ankyrin repeat domain 13 family, member D, mRNA (cDNA clone MGC:149687 IMAGE:40117420), complete cds.
BC121025 - Homo sapiens ankyrin repeat domain 13 family, member D, mRNA (cDNA clone MGC:149688 IMAGE:40117423), complete cds.
JD071825 - Sequence 52849 from Patent EP1572962.
KJ905080 - Synthetic construct Homo sapiens clone ccsbBroadEn_14474 ANKRD13D gene, encodes complete protein.
KJ906488 - Synthetic construct Homo sapiens clone ccsbBroadEn_16158 ANKRD13D gene, encodes complete protein.
AK091614 - Homo sapiens cDNA FLJ34295 fis, clone FEBRA2005701, weakly similar to ZINC FINGER PROTEIN 195.
AX747096 - Sequence 621 from Patent EP1308459.
AK057566 - Homo sapiens cDNA FLJ33004 fis, clone THYMU1000242, weakly similar to Human transformation-related protein mRNA.
AK057681 - Homo sapiens cDNA FLJ33119 fis, clone TRACH2001395, highly similar to Ankyrin repeat domain-containing protein 13D.
AK027313 - Homo sapiens cDNA FLJ14407 fis, clone HEMBA1004295, highly similar to Ankyrin repeat domain-containing protein 13D.
BC044239 - Homo sapiens ankyrin repeat domain 13 family, member D, mRNA (cDNA clone IMAGE:5750538), complete cds.
CU692190 - Synthetic construct Homo sapiens gateway clone IMAGE:100021297 5' read ANKRD13D mRNA.
KJ906487 - Synthetic construct Homo sapiens clone ccsbBroadEn_16157 ANKRD13D gene, encodes complete protein.
JD187719 - Sequence 168743 from Patent EP1572962.
JD413707 - Sequence 394731 from Patent EP1572962.
JD191320 - Sequence 172344 from Patent EP1572962.
JD563683 - Sequence 544707 from Patent EP1572962.
JD199361 - Sequence 180385 from Patent EP1572962.
JD469534 - Sequence 450558 from Patent EP1572962.
JD048642 - Sequence 29666 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AN13D_HUMAN, D6RCN6, NR_030767, Q0VAK0, Q0VGC3, Q6ZTN6, Q6ZVD0, Q86SU1
UCSC ID: uc001okc.2
RefSeq Accession: NR_030767
Protein: Q6ZTN6 (aka AN13D_HUMAN)

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NR_030767.1
exon count: 16CDS single in 3' UTR: no RNA size: 2233
ORF size: 1557CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 3120.00frame shift in genome: no % Coverage: 99.55
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.