Description: Homo sapiens protein arginine methyltransferase 8 (PRMT8), transcript variant 2, mRNA. RefSeq Summary (NM_001256536): Arginine methylation is a widespread posttranslational modification mediated by arginine methyltransferases, such as PRMT8. Arginine methylation is involved in a number of cellular processes, including DNA repair, RNA transcription, signal transduction, protein compartmentalization, and possibly protein translation (Lee et al., 2005 [PubMed 16051612]).[supplied by OMIM, Mar 2008]. Transcript (Including UTRs) Position: hg19 chr12:3,701,390-3,703,138 Size: 1,749 Total Exon Count: 2 Strand: +
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Descriptions from all associated GenBank mRNAs
AK315619 - Homo sapiens cDNA, FLJ96700, highly similar to Homo sapiens HMT1 hnRNP methyltransferase-like 4 (S. cerevisiae)(HRMT1L4), mRNA. AB209027 - Homo sapiens mRNA for Protein arginine N-methyltransferase 4 variant protein. BC022458 - Homo sapiens protein arginine methyltransferase 8, mRNA (cDNA clone MGC:26069 IMAGE:4796524), complete cds. AB590500 - Synthetic construct DNA, clone: pFN21AE1873, Homo sapiens PRMT8 gene for protein arginine methyltransferase 8, without stop codon, in Flexi system. AK026786 - Homo sapiens cDNA: FLJ23133 fis, clone LNG08560. AF263539 - Homo sapiens arginine N-methyltransferase (HRMT1L3) mRNA, complete cds. DQ892381 - Synthetic construct clone IMAGE:100005011; FLH185782.01X; RZPDo839E12148D protein arginine methyltransferase 8 (PRMT8) gene, encodes complete protein. DQ895593 - Synthetic construct Homo sapiens clone IMAGE:100010053; FLH185778.01L; RZPDo839E12147D protein arginine methyltransferase 8 (PRMT8) gene, encodes complete protein. KJ902909 - Synthetic construct Homo sapiens clone ccsbBroadEn_12303 PRMT8 gene, encodes complete protein. AK093651 - Homo sapiens cDNA FLJ36332 fis, clone THYMU2006098, highly similar to Homo sapiens arginine N-methyltransferase (HRMT1L3) mRNA. JD196623 - Sequence 177647 from Patent EP1572962. JD092826 - Sequence 73850 from Patent EP1572962. JD389160 - Sequence 370184 from Patent EP1572962. JD316636 - Sequence 297660 from Patent EP1572962. JD132332 - Sequence 113356 from Patent EP1572962. JD398238 - Sequence 379262 from Patent EP1572962. JD287407 - Sequence 268431 from Patent EP1572962. JD176995 - Sequence 158019 from Patent EP1572962. JD286170 - Sequence 267194 from Patent EP1572962. JD150062 - Sequence 131086 from Patent EP1572962. JD144425 - Sequence 125449 from Patent EP1572962.