Human Gene FAM234B (uc001rbi.3)
  Description: Homo sapiens FAM234B (FAM234B), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr12:13,197,315-13,236,383 Size: 39,069 Total Exon Count: 13 Strand: +
Coding Region
   Position: hg19 chr12:13,197,338-13,233,564 Size: 36,227 Coding Exon Count: 13 

Page IndexSequence and LinksUniProtKB CommentsPrimersGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:13,197,315-13,236,383)mRNA (may differ from genome)Protein (622 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVLynxMGIneXtProtOMIMPubMed
TreefamUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: K1467_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein KIAA1467;
SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential).
SIMILARITY: Belongs to the ITFG3 family.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 15.24 RPKM in Brain - Cerebellar Hemisphere
Total median expression: 174.87 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -3.1023-0.135 Picture PostScript Text
3' UTR -854.232819-0.303 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR011047 - Quinonprotein_ADH-like

SCOP Domains:
50998 - Quinoprotein alcohol dehydrogenase-like

ModBase Predicted Comparative 3D Structure on A2RU67
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserGenome BrowserNo orthologNo ortholog
Gene Details  Gene Details  
Gene Sorter  Gene Sorter  
  EnsemblFlyBase  
  Protein SequenceProtein Sequence  
  AlignmentAlignment  

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  LF207435 - JP 2014500723-A/14938: Polycomb-Associated Non-Coding RNAs.
AL832902 - Homo sapiens mRNA; cDNA DKFZp762C0813 (from clone DKFZp762C0813).
MA443012 - JP 2018138019-A/14938: Polycomb-Associated Non-Coding RNAs.
BC132772 - Homo sapiens KIAA1467, mRNA (cDNA clone MGC:164403 IMAGE:40146794), complete cds.
BC132774 - Homo sapiens KIAA1467, mRNA (cDNA clone MGC:164405 IMAGE:40146796), complete cds.
AK125278 - Homo sapiens cDNA FLJ43288 fis, clone MESAN2012054.
BC039267 - Homo sapiens KIAA1467, mRNA (cDNA clone MGC:33919 IMAGE:5274878), complete cds.
CR936647 - Homo sapiens mRNA; cDNA DKFZp781O012 (from clone DKFZp781O012).
HQ258331 - Synthetic construct Homo sapiens clone IMAGE:100072640 KIAA1467 (KIAA1467) gene, encodes complete protein.
HQ258475 - Synthetic construct Homo sapiens clone IMAGE:100072904 KIAA1467 (KIAA1467) gene, encodes complete protein.
KJ899353 - Synthetic construct Homo sapiens clone ccsbBroadEn_08747 KIAA1467 gene, encodes complete protein.
KJ899354 - Synthetic construct Homo sapiens clone ccsbBroadEn_08748 KIAA1467 gene, encodes complete protein.
KJ906281 - Synthetic construct Homo sapiens clone ccsbBroadEn_15951 KIAA1467 gene, encodes complete protein.
LF366136 - JP 2014500723-A/173639: Polycomb-Associated Non-Coding RNAs.
LF366137 - JP 2014500723-A/173640: Polycomb-Associated Non-Coding RNAs.
LF366138 - JP 2014500723-A/173641: Polycomb-Associated Non-Coding RNAs.
AB040900 - Homo sapiens mRNA for KIAA1467 protein, partial cds.
AK294732 - Homo sapiens cDNA FLJ50146 complete cds.
DQ573050 - Homo sapiens piRNA piR-41162, complete sequence.
LF366143 - JP 2014500723-A/173646: Polycomb-Associated Non-Coding RNAs.
LF366145 - JP 2014500723-A/173648: Polycomb-Associated Non-Coding RNAs.
LF366146 - JP 2014500723-A/173649: Polycomb-Associated Non-Coding RNAs.
LF366147 - JP 2014500723-A/173650: Polycomb-Associated Non-Coding RNAs.
JD186947 - Sequence 167971 from Patent EP1572962.
JD539417 - Sequence 520441 from Patent EP1572962.
LF366148 - JP 2014500723-A/173651: Polycomb-Associated Non-Coding RNAs.
JD559344 - Sequence 540368 from Patent EP1572962.
JD367519 - Sequence 348543 from Patent EP1572962.
JD533909 - Sequence 514933 from Patent EP1572962.
JD435428 - Sequence 416452 from Patent EP1572962.
JD308132 - Sequence 289156 from Patent EP1572962.
JD254663 - Sequence 235687 from Patent EP1572962.
JD321541 - Sequence 302565 from Patent EP1572962.
JD235754 - Sequence 216778 from Patent EP1572962.
BC030126 - Homo sapiens cDNA clone IMAGE:4817390.
JD328428 - Sequence 309452 from Patent EP1572962.
MA601713 - JP 2018138019-A/173639: Polycomb-Associated Non-Coding RNAs.
MA601714 - JP 2018138019-A/173640: Polycomb-Associated Non-Coding RNAs.
MA601715 - JP 2018138019-A/173641: Polycomb-Associated Non-Coding RNAs.
MA601720 - JP 2018138019-A/173646: Polycomb-Associated Non-Coding RNAs.
MA601722 - JP 2018138019-A/173648: Polycomb-Associated Non-Coding RNAs.
MA601723 - JP 2018138019-A/173649: Polycomb-Associated Non-Coding RNAs.
MA601724 - JP 2018138019-A/173650: Polycomb-Associated Non-Coding RNAs.
MA601725 - JP 2018138019-A/173651: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: A2RU67, K1467_HUMAN, KIAA1467, NM_020853, NP_065904, Q49AF2, Q5CZ81, Q6ZUV7, Q9P261
UCSC ID: uc001rbi.3
RefSeq Accession: NM_020853
Protein: A2RU67 (aka K1467_HUMAN)
CCDS: CCDS31750.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_020853.1
exon count: 13CDS single in 3' UTR: no RNA size: 4725
ORF size: 1869CDS single in intron: no Alignment % ID: 99.98
txCdsPredict score: 3938.00frame shift in genome: no % Coverage: 99.70
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.