Human Gene IKBIP (uc001tfx.4)
  Description: Homo sapiens IKBKB interacting protein (IKBIP), transcript variant 1, mRNA.
Transcript (Including UTRs)
   Position: hg19 chr12:99,018,030-99,038,829 Size: 20,800 Total Exon Count: 3 Strand: -
Coding Region
   Position: hg19 chr12:99,019,708-99,038,479 Size: 18,772 Coding Exon Count: 3 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:99,018,030-99,038,829)mRNA (may differ from genome)Protein (377 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCHPRDLynxMalacards
MGIOMIMPubMedUniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: IKBIP
Diseases sorted by gene-association score: andersen syndrome (7)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 19.11 RPKM in Cells - Cultured fibroblasts
Total median expression: 128.02 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -162.80350-0.465 Picture PostScript Text
3' UTR -424.611678-0.253 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q70UQ0-4
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserGenome BrowserNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGDEnsembl   
 Protein SequenceProtein Sequence   
 AlignmentAlignment   

-  Descriptions from all associated GenBank mRNAs
  BC051372 - Homo sapiens IKK interacting protein, mRNA (cDNA clone IMAGE:6575635), complete cds.
AJ539426 - Homo sapiens mRNA for IKIP2 (IKIP gene).
AJ539427 - Homo sapiens mRNA for IKIP3 (IKIP gene).
AK123069 - Homo sapiens cDNA FLJ41074 fis, clone 3NB692008729.
BC107572 - Homo sapiens IKK interacting protein, mRNA (cDNA clone IMAGE:3685751), partial cds.
BC029415 - Homo sapiens IKK interacting protein, mRNA (cDNA clone IMAGE:4772912), complete cds.
AJ539425 - Homo sapiens mRNA for IKIP1 (IKIP gene).
BC058933 - Homo sapiens IKK interacting protein, mRNA (cDNA clone MGC:65157 IMAGE:5541278), complete cds.
JD211868 - Sequence 192892 from Patent EP1572962.
JD159661 - Sequence 140685 from Patent EP1572962.
AK055613 - Homo sapiens cDNA FLJ31051 fis, clone HSYRA2000605, weakly similar to MYOSIN HEAVY CHAIN, CLONE 203.
JD410467 - Sequence 391491 from Patent EP1572962.
JD350760 - Sequence 331784 from Patent EP1572962.
JD404583 - Sequence 385607 from Patent EP1572962.
JD344146 - Sequence 325170 from Patent EP1572962.
JD344145 - Sequence 325169 from Patent EP1572962.
JD235288 - Sequence 216312 from Patent EP1572962.
JD251655 - Sequence 232679 from Patent EP1572962.
JD236343 - Sequence 217367 from Patent EP1572962.
JD236810 - Sequence 217834 from Patent EP1572962.
JD519655 - Sequence 500679 from Patent EP1572962.
JD535982 - Sequence 517006 from Patent EP1572962.
JD315650 - Sequence 296674 from Patent EP1572962.
JD287364 - Sequence 268388 from Patent EP1572962.
JD304604 - Sequence 285628 from Patent EP1572962.
JD037554 - Sequence 18578 from Patent EP1572962.
JD051997 - Sequence 33021 from Patent EP1572962.
HQ448064 - Synthetic construct Homo sapiens clone IMAGE:100071443; CCSB011952_01 IKK interacting protein (IKIP) gene, encodes complete protein.
KJ895358 - Synthetic construct Homo sapiens clone ccsbBroadEn_04752 IKBIP gene, encodes complete protein.
CU691338 - Synthetic construct Homo sapiens gateway clone IMAGE:100021677 5' read IKIP mRNA.
JD525159 - Sequence 506183 from Patent EP1572962.
JD251227 - Sequence 232251 from Patent EP1572962.
JD218450 - Sequence 199474 from Patent EP1572962.
JD394087 - Sequence 375111 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: IKIP, NM_153687, NP_710154, Q70UQ0-4, uc001tfx.3
UCSC ID: uc001tfx.4
RefSeq Accession: NM_153687
Protein: Q70UQ0-4, splice isoform of Q70UQ0 CCDS: CCDS9068.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_153687.3
exon count: 3CDS single in 3' UTR: no RNA size: 3175
ORF size: 1134CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2312.00frame shift in genome: no % Coverage: 99.59
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.