Human Gene SART3 (uc001tnb.3)
  Description: RecName: Full=Squamous cell carcinoma antigen recognized by T-cells 3; Short=SART-3; Short=hSART-3; AltName: Full=Tat-interacting protein of 110 kDa; Short=Tip110;
Transcript (Including UTRs)
   Position: hg19 chr12:108,953,993-108,955,176 Size: 1,184 Total Exon Count: 1 Strand: -
Coding Region
   Position: hg19 chr12:108,954,541-108,954,930 Size: 390 Coding Exon Count: 1 

Page IndexSequence and LinksPrimersMalaCardsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:108,953,993-108,955,176)mRNA (may differ from genome)Protein (129 aa)
Gene SorterGenome BrowserOther Species FASTAGene interactionsTable SchemaAlphaFold
EnsemblExonPrimerGeneCardsHGNCLynxMalacards
MGIPubMedUniProtKBWikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  MalaCards Disease Associations
  MalaCards Gene Search: SART3
Diseases sorted by gene-association score: hiv-1 (11), porokeratosis (10), squamous cell carcinoma (5)

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 26.26 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 552.99 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -77.80246-0.316 Picture PostScript Text
3' UTR -155.60548-0.284 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q15020-3
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AB020880 - Homo sapiens mRNA for squamous cell carcinoma antigen SART-3, complete cds.
D63879 - Homo sapiens mRNA for KIAA0156 gene, complete cds.
AF387506 - Homo sapiens KIAA0156 isoform mRNA, complete cds.
AK290209 - Homo sapiens cDNA FLJ76238 complete cds, highly similar to Homo sapiens squamous cell carcinoma antigen recognised by T cells 3 (SART3), mRNA.
BC093784 - Homo sapiens squamous cell carcinoma antigen recognized by T cells 3, mRNA (cDNA clone MGC:120819 IMAGE:7939629), complete cds.
BC111983 - Homo sapiens squamous cell carcinoma antigen recognized by T cells 3, mRNA (cDNA clone MGC:138188 IMAGE:8327451), complete cds.
BC143253 - Homo sapiens squamous cell carcinoma antigen recognized by T cells 3, mRNA (cDNA clone MGC:176772 IMAGE:9051755), complete cds.
KJ898083 - Synthetic construct Homo sapiens clone ccsbBroadEn_07477 SART3 gene, encodes complete protein.
KR712178 - Synthetic construct Homo sapiens clone CCSBHm_00036630 SART3 (SART3) mRNA, encodes complete protein.
AB385287 - Synthetic construct DNA, clone: pF1KA0156, Homo sapiens SART3 gene for squamous cell carcinoma antigen recognized by T-cells 3, complete cds, without stop codon, in Flexi system.
AK225174 - Homo sapiens mRNA for squamous cell carcinoma antigen recognized by T cells 3 variant, clone: CBR08707.
AK304834 - Homo sapiens cDNA FLJ51777 complete cds, highly similar to Squamous cell carcinoma antigen recognized byT-cells 3.
BC103706 - Homo sapiens squamous cell carcinoma antigen recognized by T cells 3, mRNA (cDNA clone IMAGE:6162918), partial cds.
BC004547 - Homo sapiens squamous cell carcinoma antigen recognised by T cells 3, mRNA (cDNA clone IMAGE:3958574), partial cds.
BC024279 - Homo sapiens squamous cell carcinoma antigen recognized by T cells 3, mRNA (cDNA clone IMAGE:4810833), with apparent retained intron.
BC032601 - Homo sapiens squamous cell carcinoma antigen recognized by T cells 3, mRNA (cDNA clone IMAGE:5534381), partial cds.
BC015627 - Homo sapiens squamous cell carcinoma antigen recognized by T cells 3, mRNA (cDNA clone IMAGE:4844039), with apparent retained intron.
BC041638 - Homo sapiens squamous cell carcinoma antigen recognized by T cells 3, mRNA (cDNA clone IMAGE:4844061), complete cds.

-  Other Names for This Gene
  Alternate Gene Symbols: BC041638, KIAA0156, Q15020-3, TIP110
UCSC ID: uc001tnb.3
Representative RNA: BC041638
Protein: Q15020-3, splice isoform of Q15020

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: BC041638.1
exon count: 1CDS single in 3' UTR: no RNA size: 1217
ORF size: 390CDS single in intron: no Alignment % ID: 99.66
txCdsPredict score: 802.00frame shift in genome: no % Coverage: 97.29
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.