Description: Homo sapiens dehydrogenase/reductase (SDR family) member 1 (DHRS1), transcript variant 2, mRNA. RefSeq Summary (NM_138452): This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded enzyme contains a conserved catalytic domain and likely functions as an oxidoreductase. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008]. Transcript (Including UTRs) Position: hg19 chr14:24,759,804-24,768,666 Size: 8,863 Total Exon Count: 9 Strand: - Coding Region Position: hg19 chr14:24,760,065-24,768,312 Size: 8,248 Coding Exon Count: 8
ID:DHRS1_HUMAN DESCRIPTION: RecName: Full=Dehydrogenase/reductase SDR family member 1; EC=1.1.-.-; TISSUE SPECIFICITY: Detected in heart and liver, and at low levels in skeletal muscle, kidney and pancreas. SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q96LJ7
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.