Description: Homo sapiens dynein, cytoplasmic 1, heavy chain 1 (DYNC1H1), mRNA. RefSeq Summary (NM_001376): Dyneins are a group of microtubule-activated ATPases that function as molecular motors. They are divided into two subgroups of axonemal and cytoplasmic dyneins. The cytoplasmic dyneins function in intracellular motility, including retrograde axonal transport, protein sorting, organelle movement, and spindle dynamics. Molecules of conventional cytoplasmic dynein are comprised of 2 heavy chain polypeptides and a number of intermediate and light chains.This gene encodes a member of the cytoplasmic dynein heavy chain family. [provided by RefSeq, Oct 2008]. Transcript (Including UTRs) Position: hg19 chr14:102,481,442-102,490,140 Size: 8,699 Total Exon Count: 8 Strand: + Coding Region Position: hg19 chr14:102,482,740-102,489,271 Size: 6,532 Coding Exon Count: 7
Menopause Lisette Stolk et al. Nature genetics 2009, Loci at chromosomes 13, 19 and 20 influence age at natural menopause., Nature genetics.
[PubMed 19448619]
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
