Human Gene RP11-566D24.2 (uc002adw.1)
Description: Homo sapiens zinc finger protein 280D (RP11-566D24.2), transcript variant 2, mRNA.
Transcript (Including UTRs)
Position: hg19 chr15:56,945,019-57,210,697 Size: 265,679 Total Exon Count: 24 Strand: -
Coding Region
Position: hg19 chr15:56,945,691-57,017,112 Size: 71,422 Coding Exon Count: 18
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: H0YL38_HUMAN
DESCRIPTION: SubName: Full=Zinc finger protein 280D;
CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
Primer design for this transcript
Common Gene Haplotype Alleles
Press "+" in the title bar above to open this section.
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
Press "+" in the title bar above to open this section.
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR025243 - DUF4195
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
Pfam Domains: PF13836 - Domain of unknown function (DUF4195)
PF13912 - C2H2-type zinc finger
SCOP Domains: 57667 - C2H2 and C2HC zinc fingers
ModBase Predicted Comparative 3D Structure on H0YL38
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0003676 nucleic acid binding
Descriptions from all associated GenBank mRNAs
LF208550 - JP 2014500723-A/16053: Polycomb-Associated Non-Coding RNAs.BC040532 - Homo sapiens zinc finger protein 280D, mRNA (cDNA clone IMAGE:5261474).BX641000 - Homo sapiens mRNA; cDNA DKFZp686H13148 (from clone DKFZp686H13148); complete cds.AB046804 - Homo sapiens KIAA1584 mRNA for KIAA1584 protein.BC130451 - Homo sapiens zinc finger protein 280D, mRNA (cDNA clone MGC:163323 IMAGE:40146482), complete cds.BC136412 - Homo sapiens zinc finger protein 280D, mRNA (cDNA clone MGC:168023 IMAGE:9020400), complete cds.BX640707 - Homo sapiens mRNA; cDNA DKFZp686F11161 (from clone DKFZp686F11161); complete cds.AK295159 - Homo sapiens cDNA FLJ56078 complete cds, highly similar to Suppressor of hairy wing homolog 4.AK289739 - Homo sapiens cDNA FLJ76213 complete cds, highly similar to Homo sapiens suppressor of hairy wing homolog 4 (Drosophila) (SUHW4), transcript variant 2, mRNA.AM392650 - Synthetic construct Homo sapiens clone IMAGE:100002534 for hypothetical protein (SUHW4 gene).AM393745 - Synthetic construct Homo sapiens clone IMAGE:100002533 for hypothetical protein (SUHW4 gene).BX640637 - Homo sapiens mRNA; cDNA DKFZp779P138 (from clone DKFZp779P138); complete cds.BC036541 - Homo sapiens cDNA clone IMAGE:4829311.AK310882 - Homo sapiens cDNA, FLJ17924.BC064359 - Homo sapiens zinc finger protein 280D, mRNA (cDNA clone IMAGE:5531919), complete cds.BC053649 - Homo sapiens zinc finger protein 280D, mRNA (cDNA clone IMAGE:5538785), complete cds.MA444127 - JP 2018138019-A/16053: Polycomb-Associated Non-Coding RNAs.AK000093 - Homo sapiens cDNA FLJ20086 fis, clone COL03629.AB385484 - Synthetic construct DNA, clone: pF1KA1584, Homo sapiens SUHW4 gene for suppressor of hairy wing homolog 4, complete cds, without stop codon, in Flexi system.AK025073 - Homo sapiens cDNA: FLJ21420 fis, clone COL04105.LF377622 - JP 2014500723-A/185125: Polycomb-Associated Non-Coding RNAs.JD082130 - Sequence 63154 from Patent EP1572962.BC015382 - Homo sapiens zinc finger protein 280D, mRNA (cDNA clone IMAGE:4413086), complete cds.LF377617 - JP 2014500723-A/185120: Polycomb-Associated Non-Coding RNAs.MA613199 - JP 2018138019-A/185125: Polycomb-Associated Non-Coding RNAs.MA613194 - JP 2018138019-A/185120: Polycomb-Associated Non-Coding RNAs.AK056606 - Homo sapiens cDNA FLJ32044 fis, clone NTONG2000985.AK096657 - Homo sapiens cDNA FLJ39338 fis, clone OCBBF2017899.JD188769 - Sequence 169793 from Patent EP1572962.JD337632 - Sequence 318656 from Patent EP1572962.JD310708 - Sequence 291732 from Patent EP1572962.JD361556 - Sequence 342580 from Patent EP1572962.JD524341 - Sequence 505365 from Patent EP1572962.JD363450 - Sequence 344474 from Patent EP1572962.BC063546 - Homo sapiens cDNA clone IMAGE:4755015, partial cds.JD425213 - Sequence 406237 from Patent EP1572962.JD071512 - Sequence 52536 from Patent EP1572962.JD338945 - Sequence 319969 from Patent EP1572962.JD062124 - Sequence 43148 from Patent EP1572962.JD565120 - Sequence 546144 from Patent EP1572962.JD358517 - Sequence 339541 from Patent EP1572962.JD414105 - Sequence 395129 from Patent EP1572962.JD438120 - Sequence 419144 from Patent EP1572962.JD313457 - Sequence 294481 from Patent EP1572962.JD345819 - Sequence 326843 from Patent EP1572962.JD179797 - Sequence 160821 from Patent EP1572962.JD129840 - Sequence 110864 from Patent EP1572962.JD223184 - Sequence 204208 from Patent EP1572962.JD476369 - Sequence 457393 from Patent EP1572962.JD196042 - Sequence 177066 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: BC036541, H0YL38, H0YL38_HUMAN, NM_001002843, NP_001002843, ZNF280DUCSC ID: uc002adw.1RefSeq Accession: NM_001002843
Protein: H0YL38
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
BC036541.1
exon count:
24 CDS single in 3' UTR:
no
RNA size:
4811
ORF size:
2367 CDS single in intron:
no
Alignment % ID:
99.94
txCdsPredict score:
4014.50 frame shift in genome:
no
% Coverage:
96.53
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
Click here
for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
Click here
for details on how this gene model was made and data restrictions if any.