The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9NTJ4
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0005975 carbohydrate metabolic process GO:0006013 mannose metabolic process GO:0006517 protein deglycosylation GO:0008152 metabolic process GO:0009313 oligosaccharide catabolic process
BX647111 - Homo sapiens mRNA; cDNA DKFZp686K24244 (from clone DKFZp686K24244). LF208510 - JP 2014500723-A/16013: Polycomb-Associated Non-Coding RNAs. U37248 - Homo sapiens alpha-mannosidase (6A8) mRNA, complete cds. AF044414 - Homo sapiens alpha mannosidase 6A8B (6a8b) mRNA, complete cds. AL136876 - Homo sapiens mRNA; cDNA DKFZp434D175 (from clone DKFZp434D175). BC080191 - Homo sapiens mannosidase, alpha, class 2C, member 1, mRNA (cDNA clone MGC:87979 IMAGE:6149811), complete cds. BC050550 - Homo sapiens mannosidase, alpha, class 2C, member 1, mRNA (cDNA clone MGC:57644 IMAGE:5529534), complete cds. BC038594 - Homo sapiens mannosidase, alpha, class 2C, member 1, mRNA (cDNA clone IMAGE:5527998), containing frame-shift errors. HM005428 - Homo sapiens clone HTL-T-115 testicular tissue protein Li 115 mRNA, complete cds. AK225145 - Homo sapiens mRNA for mannosidase, alpha, class 2C, member 1 variant, clone: CBL07522. AK301170 - Homo sapiens cDNA FLJ60004 complete cds, highly similar to Alpha-mannosidase 2C1 (EC 3.2.1.24). JD504146 - Sequence 485170 from Patent EP1572962. JD152754 - Sequence 133778 from Patent EP1572962. KJ891578 - Synthetic construct Homo sapiens clone ccsbBroadEn_00972 MAN2C1 gene, encodes complete protein. AB209141 - Homo sapiens mRNA for mannosidase, alpha, class 2C, member 1 variant protein. CR936817 - Homo sapiens mRNA; cDNA DKFZp686E23167 (from clone DKFZp686E23167). AK311065 - Homo sapiens cDNA, FLJ18107. LF377194 - JP 2014500723-A/184697: Polycomb-Associated Non-Coding RNAs. AK294892 - Homo sapiens cDNA FLJ57925 complete cds, highly similar to Alpha-mannosidase 2C1 (EC 3.2.1.24). CU690718 - Synthetic construct Homo sapiens gateway clone IMAGE:100023184 5' read MAN2C1 mRNA. AK295265 - Homo sapiens cDNA FLJ59120 complete cds, moderately similar to Alpha-mannosidase 2C1 (EC 3.2.1.24). MA444087 - JP 2018138019-A/16013: Polycomb-Associated Non-Coding RNAs. MA612771 - JP 2018138019-A/184697: Polycomb-Associated Non-Coding RNAs.
Biochemical and Signaling Pathways
KEGG - Kyoto Encyclopedia of Genes and Genomes hsa00511 - Other glycan degradation
BioCarta from NCI Cancer Genome Anatomy Project h_aMANpathway - Steps in the Glycosylation of Mammalian N-linked Oligosaccarides h_eradPathway - ER¿associated degradation (ERAD) Pathway
Reactome (by CSHL, EBI, and GO)
Protein Q9NTJ4 (Reactome details) participates in the following event(s):