Human Gene TBC1D2B (uc002bda.3)
Description: Homo sapiens TBC1 domain family, member 2B (TBC1D2B), transcript variant 2, mRNA.
Transcript (Including UTRs)
Position: hg19 chr15:78,294,840-78,309,628 Size: 14,789 Total Exon Count: 4 Strand: -
Coding Region
Position: hg19 chr15:78,295,638-78,309,018 Size: 13,381 Coding Exon Count: 4
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): TBC1D2B
CDC HuGE Published Literature: TBC1D2B
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00566 - Rab-GTPase-TBC domain
SCOP Domains: 47923 - Ypt/Rab-GAP domain of gyp1p
ModBase Predicted Comparative 3D Structure on Q9UPU7-3
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Descriptions from all associated GenBank mRNAs
BC033712 - Homo sapiens TBC1 domain family, member 2B, mRNA (cDNA clone IMAGE:4400762), complete cds.BC152465 - Homo sapiens TBC1 domain family, member 2B, mRNA (cDNA clone MGC:176722 IMAGE:8862601), complete cds.AB028978 - Homo sapiens mRNA for KIAA1055 protein, partial cds.BC140766 - Homo sapiens TBC1 domain family, member 2B, mRNA (cDNA clone MGC:176443 IMAGE:9021634), complete cds.BC144482 - Homo sapiens TBC1 domain family, member 2B, mRNA (cDNA clone MGC:178026 IMAGE:9053009), complete cds.KJ902282 - Synthetic construct Homo sapiens clone ccsbBroadEn_11676 TBC1D2B gene, encodes complete protein.AB463304 - Synthetic construct DNA, clone: pF1KB9777, Homo sapiens TBC1D2B gene for TBC1 domain family, member 2B, without stop codon, in Flexi system.LF208576 - JP 2014500723-A/16079: Polycomb-Associated Non-Coding RNAs.AK000173 - Homo sapiens cDNA FLJ20166 fis, clone COL09511.JD425287 - Sequence 406311 from Patent EP1572962.JD425286 - Sequence 406310 from Patent EP1572962.JD425289 - Sequence 406313 from Patent EP1572962.LF378054 - JP 2014500723-A/185557: Polycomb-Associated Non-Coding RNAs.LF378056 - JP 2014500723-A/185559: Polycomb-Associated Non-Coding RNAs.DQ574184 - Homo sapiens piRNA piR-42296, complete sequence.JD206975 - Sequence 187999 from Patent EP1572962.MA444153 - JP 2018138019-A/16079: Polycomb-Associated Non-Coding RNAs.MA613631 - JP 2018138019-A/185557: Polycomb-Associated Non-Coding RNAs.MA613633 - JP 2018138019-A/185559: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: AK000173, KIAA1055, NM_015079, NP_055894, Q9UPU7-3UCSC ID: uc002bda.3RefSeq Accession: NM_015079
Protein: Q9UPU7-3 , splice isoform of Q9UPU7
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
AK000173.1
exon count:
4 CDS single in 3' UTR:
no
RNA size:
2364
ORF size:
939 CDS single in intron:
no
Alignment % ID:
99.96
txCdsPredict score:
1642.00 frame shift in genome:
no
% Coverage:
99.28
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
1354 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.