Human Gene TVP23C (uc002goq.2)
Description: Homo sapiens trans-golgi network vesicle protein 23 homolog C (S. cerevisiae) (TVP23C), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr17:15,405,578-15,466,945 Size: 61,368 Total Exon Count: 6 Strand: -
Coding Region
Position: hg19 chr17:15,406,178-15,466,762 Size: 60,585 Coding Exon Count: 6
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: F18B2_HUMAN
DESCRIPTION: RecName: Full=Protein FAM18B2;
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein (Potential).SIMILARITY: Belongs to the FAM18/TVP23 family.
Primer design for this transcript
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR008564 - DUF846_euk
Pfam Domains: PF05832 - Eukaryotic protein of unknown function (DUF846)
ModBase Predicted Comparative 3D Structure on Q96ET8
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AB074181 - Homo sapiens primary neuroblastoma cDNA, clone:Nbla10383, full insert sequence.AK303475 - Homo sapiens cDNA FLJ53614 complete cds, highly similar to Protein FAM18B.BC011952 - Homo sapiens family with sequence similarity 18, member B2, mRNA (cDNA clone MGC:8763 IMAGE:3860433), complete cds.AK310363 - Homo sapiens cDNA, FLJ17405.LF326224 - JP 2014500723-A/133727: Polycomb-Associated Non-Coding RNAs.JD100533 - Sequence 81557 from Patent EP1572962.JD387192 - Sequence 368216 from Patent EP1572962.JD545879 - Sequence 526903 from Patent EP1572962.JD434011 - Sequence 415035 from Patent EP1572962.JD330527 - Sequence 311551 from Patent EP1572962.JD204510 - Sequence 185534 from Patent EP1572962.JD265013 - Sequence 246037 from Patent EP1572962.JD214474 - Sequence 195498 from Patent EP1572962.JD064280 - Sequence 45304 from Patent EP1572962.JD065557 - Sequence 46581 from Patent EP1572962.JD204924 - Sequence 185948 from Patent EP1572962.LF326223 - JP 2014500723-A/133726: Polycomb-Associated Non-Coding RNAs.KJ900417 - Synthetic construct Homo sapiens clone ccsbBroadEn_09811 FAM18B2 gene, encodes complete protein.DQ579005 - Homo sapiens piRNA piR-47117, complete sequence.LF326214 - JP 2014500723-A/133717: Polycomb-Associated Non-Coding RNAs.LF326212 - JP 2014500723-A/133715: Polycomb-Associated Non-Coding RNAs.MA561801 - JP 2018138019-A/133727: Polycomb-Associated Non-Coding RNAs.MA561800 - JP 2018138019-A/133726: Polycomb-Associated Non-Coding RNAs.MA561791 - JP 2018138019-A/133717: Polycomb-Associated Non-Coding RNAs.MA561789 - JP 2018138019-A/133715: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: F18B2_HUMAN, FAM18B2, Nbla10383, NM_145301, NP_660344, Q3LIC7, Q96ET8UCSC ID: uc002goq.2RefSeq Accession: NM_145301
Protein: Q96ET8
(aka F18B2_HUMAN)
CCDS: CCDS11170.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_145301.2
exon count:
6 CDS single in 3' UTR:
no
RNA size:
1632
ORF size:
831 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1527.00 frame shift in genome:
no
% Coverage:
98.90
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
834 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.