Human Gene ANKRD13B (uc002hei.3)
Description: Homo sapiens ankyrin repeat domain 13B (ANKRD13B), mRNA.
Transcript (Including UTRs)
Position: hg19 chr17:27,920,527-27,941,779 Size: 21,253 Total Exon Count: 15 Strand: +
Coding Region
Position: hg19 chr17:27,920,640-27,940,600 Size: 19,961 Coding Exon Count: 15
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: AN13B_HUMAN
DESCRIPTION: RecName: Full=Ankyrin repeat domain-containing protein 13B;
SIMILARITY: Contains 2 ANK repeats.SIMILARITY: Contains 3 UIM (ubiquitin-interacting motif) repeats.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR021832 - ANKRD13
IPR002110 - Ankyrin_rpt
IPR020683 - Ankyrin_rpt-contain_dom
IPR003903 - Ubiquitin-int_motif
Pfam Domains: PF00023 - Ankyrin repeat
PF02809 - Ubiquitin interaction motif
PF11904 - GPCR-chaperone
PF12796 - Ankyrin repeats (3 copies)
PF13606 - Ankyrin repeat
PF13637 - Ankyrin repeats (many copies)
PF13857 - Ankyrin repeats (many copies)
SCOP Domains: 48403 - Ankyrin repeat
ModBase Predicted Comparative 3D Structure on Q86YJ7
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
LF209201 - JP 2014500723-A/16704: Polycomb-Associated Non-Coding RNAs.BC062597 - Homo sapiens ankyrin repeat domain 13B, mRNA (cDNA clone IMAGE:5247577), partial cds.MA444778 - JP 2018138019-A/16704: Polycomb-Associated Non-Coding RNAs.LF212411 - JP 2014500723-A/19914: Polycomb-Associated Non-Coding RNAs.AK092673 - Homo sapiens cDNA FLJ35354 fis, clone PUAEN2000080, highly similar to Ankyrin repeat domain-containing protein 13B.AX747664 - Sequence 1189 from Patent EP1308459.AK097716 - Homo sapiens cDNA FLJ40397 fis, clone TESTI2037002.AK098421 - Homo sapiens cDNA FLJ25555 fis, clone JTH02535.AK000425 - Homo sapiens cDNA FLJ20418 fis, clone KAT02427.JD405126 - Sequence 386150 from Patent EP1572962.JD535147 - Sequence 516171 from Patent EP1572962.JD157952 - Sequence 138976 from Patent EP1572962.JD229533 - Sequence 210557 from Patent EP1572962.JD117884 - Sequence 98908 from Patent EP1572962.JD225181 - Sequence 206205 from Patent EP1572962.JD110791 - Sequence 91815 from Patent EP1572962.JD329317 - Sequence 310341 from Patent EP1572962.JD151783 - Sequence 132807 from Patent EP1572962.JD115566 - Sequence 96590 from Patent EP1572962.JD257931 - Sequence 238955 from Patent EP1572962.JD503644 - Sequence 484668 from Patent EP1572962.JD128348 - Sequence 109372 from Patent EP1572962.JD080951 - Sequence 61975 from Patent EP1572962.JD214849 - Sequence 195873 from Patent EP1572962.MA447988 - JP 2018138019-A/19914: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: AN13B_HUMAN, NM_152345, NP_689558, Q86YJ7, Q8N7S9UCSC ID: uc002hei.3RefSeq Accession: NM_152345
Protein: Q86YJ7
(aka AN13B_HUMAN)
CCDS: CCDS11251.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_152345.4
exon count:
15 CDS single in 3' UTR:
no
RNA size:
3203
ORF size:
1881 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
3948.00 frame shift in genome:
no
% Coverage:
99.06
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
yes
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
1042 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.