Description: Homo sapiens transmembrane protease, serine 9 (TMPRSS9), mRNA. RefSeq Summary (NM_182973): The protein encoded by this gene is a membrane-bound type II serine polyprotease that is cleaved to release three different proteases. Two of the proteases are active and can be inhibited by serine protease inhibitors, and one is thought to be catalytically inactive. This gene enhances the invasive capability of pancreatic cancer cells and may be involved in cancer progression. [provided by RefSeq, Jul 2016]. Transcript (Including UTRs) Position: hg19 chr19:2,389,784-2,414,056 Size: 24,273 Total Exon Count: 10 Strand: + Coding Region Position: hg19 chr19:2,389,784-2,414,039 Size: 24,256 Coding Exon Count: 10
ID:E7EMP4_HUMAN DESCRIPTION: SubName: Full=Serase-3; SIMILARITY: Belongs to the peptidase S1 family. CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on E7EMP4
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.