Description: Homo sapiens solute carrier family 4, anion exchanger, member 3 (SLC4A3), transcript variant 2, mRNA. RefSeq Summary (NM_201574): The protein encoded by this gene is a plasma membrane anion exchange protein. The encoded protein has been found in brain, heart, kidney, small intestine, and lung. [provided by RefSeq, May 2016]. Transcript (Including UTRs) Position: hg19 chr2:220,492,292-220,496,838 Size: 4,547 Total Exon Count: 7 Strand: + Coding Region Position: hg19 chr2:220,492,715-220,496,838 Size: 4,124 Coding Exon Count: 6
ID:F8WD49_HUMAN DESCRIPTION: SubName: Full=Anion exchange protein 3; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): SLC4A3 CDC HuGE Published Literature: SLC4A3 Positive Disease Associations: epilepsy Related Studies:
epilepsy Sander T et al. 2002, Association of the 867Asp variant of the human anion exchanger 3 gene with common subtypes of idiopathic generalized epilepsy., Epilepsy research. 2002 Oct;51(3):249-55.
[PubMed 12399075]
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on F8WD49
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
