Description: Homo sapiens ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1), transcript variant 13, non-coding RNA. RefSeq Summary (NR_047554): Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Alternatively spliced transcript variants encoding multiple isoforms have been described for this gene, and multiple pseudogenes of this gene have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Apr 2012]. Transcript (Including UTRs) Position: hg19 chr20:48,697,661-48,729,735 Size: 32,075 Total Exon Count: 3 Strand: -
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Descriptions from all associated GenBank mRNAs
BC172339 - Synthetic construct Homo sapiens clone IMAGE:100069033, MGC:199044 TMEM189-UBE2V1 readthrough transcript (TMEM189-UBE2V1) mRNA, encodes complete protein. AB587452 - Synthetic construct DNA, clone: pF1KB7917, Homo sapiens TMEM189-UBE2V1 gene for TMEM189-UBE2V1 readthrough, without stop codon, in Flexi system. U49278 - Homo sapiens UEV-1 (UBE2V) mRNA, partial cds. BX647511 - Homo sapiens mRNA; cDNA DKFZp686I21199 (from clone DKFZp686I21199). BX648147 - Homo sapiens mRNA; cDNA DKFZp686G1080 (from clone DKFZp686G1080). U97279 - Homo sapiens UEV-1 (UBE2V) alternatively spliced incompletely processed mRNA, partial cds. AL110132 - Homo sapiens mRNA; cDNA DKFZp564H192 (from clone DKFZp564H192). JD557645 - Sequence 538669 from Patent EP1572962. AF049671 - Homo sapiens clone CIR1 cell immortalization-related mRNA sequence. U39360 - Homo sapiens DNA-binding protein (CROC-1A) mRNA, complete cds. U39361 - Homo sapiens DNA-binding protein (CROC-1B) mRNA, complete cds. BC008944 - Homo sapiens ubiquitin-conjugating enzyme E2 variant 1, mRNA (cDNA clone IMAGE:2960953), partial cds. BC000468 - Homo sapiens ubiquitin-conjugating enzyme E2 variant 1, mRNA (cDNA clone MGC:8586 IMAGE:2961017), complete cds. JD273306 - Sequence 254330 from Patent EP1572962. JD101605 - Sequence 82629 from Patent EP1572962. JD315254 - Sequence 296278 from Patent EP1572962. JD558001 - Sequence 539025 from Patent EP1572962. JD272684 - Sequence 253708 from Patent EP1572962. JD299451 - Sequence 280475 from Patent EP1572962. DQ598317 - Homo sapiens piRNA piR-36383, complete sequence. JD269185 - Sequence 250209 from Patent EP1572962. JD133135 - Sequence 114159 from Patent EP1572962. JD104747 - Sequence 85771 from Patent EP1572962. JD192643 - Sequence 173667 from Patent EP1572962. JD247296 - Sequence 228320 from Patent EP1572962. JD413564 - Sequence 394588 from Patent EP1572962. JD324264 - Sequence 305288 from Patent EP1572962. JD240731 - Sequence 221755 from Patent EP1572962. JD083928 - Sequence 64952 from Patent EP1572962. JD110278 - Sequence 91302 from Patent EP1572962. JD202857 - Sequence 183881 from Patent EP1572962. JD377384 - Sequence 358408 from Patent EP1572962. JD320567 - Sequence 301591 from Patent EP1572962. JD391827 - Sequence 372851 from Patent EP1572962. JD433549 - Sequence 414573 from Patent EP1572962. JD272706 - Sequence 253730 from Patent EP1572962. JD403675 - Sequence 384699 from Patent EP1572962. JD253152 - Sequence 234176 from Patent EP1572962. JD297643 - Sequence 278667 from Patent EP1572962. JD218720 - Sequence 199744 from Patent EP1572962. JD054937 - Sequence 35961 from Patent EP1572962. JD498860 - Sequence 479884 from Patent EP1572962. JD498861 - Sequence 479885 from Patent EP1572962. JD241200 - Sequence 222224 from Patent EP1572962. JD460143 - Sequence 441167 from Patent EP1572962. JD261094 - Sequence 242118 from Patent EP1572962. JD261096 - Sequence 242120 from Patent EP1572962. JD228794 - Sequence 209818 from Patent EP1572962. JD488233 - Sequence 469257 from Patent EP1572962. JD268228 - Sequence 249252 from Patent EP1572962. JD061124 - Sequence 42148 from Patent EP1572962. BC005215 - Homo sapiens cDNA clone IMAGE:3996506. U97280 - Homo sapiens UEV1Bs (UBE2V) mRNA, alternatively spliced, partial cds. AY008273 - Homo sapiens TRAF6-regulated IKK activator 1 beta Uev1A mRNA, complete cds. U97281 - Homo sapiens UEV1As (UBE2V) mRNA, alternatively spliced, complete cds. AK314754 - Homo sapiens cDNA, FLJ95620. BT007382 - Homo sapiens ubiquitin-conjugating enzyme E2 variant 1 mRNA, complete cds. CU674232 - Synthetic construct Homo sapiens gateway clone IMAGE:100017928 5' read UBE2V1 mRNA. HQ448675 - Synthetic construct Homo sapiens clone IMAGE:100072117; CCSB004673_01 ubiquitin-conjugating enzyme E2 variant 1 (UBE2V1) gene, encodes complete protein. KJ892347 - Synthetic construct Homo sapiens clone ccsbBroadEn_01741 UBE2V1 gene, encodes complete protein.