Description: Homo sapiens chondrolectin (CHODL), transcript variant 3, mRNA. RefSeq Summary (NM_001204176): This gene encodes a type I membrane protein with a carbohydrate recognition domain characteristic of C-type lectins in its extracellular portion. In other proteins, this domain is involved in endocytosis of glycoproteins and exogenous sugar-bearing pathogens. This protein localizes predominantly to the perinuclear region. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]. Transcript (Including UTRs) Position: hg19 chr21:19,273,580-19,639,687 Size: 366,108 Total Exon Count: 7 Strand: + Coding Region Position: hg19 chr21:19,628,870-19,638,355 Size: 9,486 Coding Exon Count: 5
ID:CHODL_HUMAN DESCRIPTION: RecName: Full=Chondrolectin; AltName: Full=Transmembrane protein MT75; Flags: Precursor; SUBCELLULAR LOCATION: Cytoplasm. Membrane; Single-pass type I membrane protein (Potential). TISSUE SPECIFICITY: Found in spleen, testis, prostate and fetal liver. Expression limited to vascular muscle of testis, smooth muscle of prostate stroma, heart muscle, skeletal muscle, crypts of small intestine, and red pulp of spleen. PTM: N-glycosylated. MISCELLANEOUS: A protein of the expected size has been detected by antibody binding and Western blot in at least one of the analyzed tissues or cells (PubMed:22042635). SIMILARITY: Contains 1 C-type lectin domain. WEB RESOURCE: Name=Functional Glycomics Gateway - Glycan Binding; Note=Chondrolectin; URL="http://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Ctlect_185";
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9H9P2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
