Description: Homo sapiens carbonyl reductase 3 (CBR3), mRNA. RefSeq Summary (NM_001236): Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008]. Transcript (Including UTRs) Position: hg19 chr21:37,507,263-37,518,860 Size: 11,598 Total Exon Count: 3 Strand: + Coding Region Position: hg19 chr21:37,507,491-37,518,810 Size: 11,320 Coding Exon Count: 3
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on O75828
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006805 xenobiotic metabolic process GO:0042376 phylloquinone catabolic process GO:0050890 cognition GO:0055114 oxidation-reduction process