Cognitive performance Need ,et al. 2009, A Genome-wide Study of Common SNPs and CNVs in Cognitive Performance in the CANTAB battery, Human molecular genetics 2009 18- 23 : 4650-61.
[PubMed 19734545]
Psychomotor Performance Anna C Need et al. Human molecular genetics 2009, A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB., Human molecular genetics.
[PubMed 19734545]
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00595 - PDZ domain (Also known as DHR or GLGF)
ModBase Predicted Comparative 3D Structure on Q9C0E4-3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
AB051506 - Homo sapiens KIAA1719 mRNA for KIAA1719 protein. AB384271 - Synthetic construct DNA, clone: pF1KSDA1719, Homo sapiens GRIP2 gene for glutamate receptor interacting protein 2, complete cds, without stop codon, in Flexi system. JD088796 - Sequence 69820 from Patent EP1572962. AK074145 - Homo sapiens mRNA for FLJ00218 protein. AK095762 - Homo sapiens cDNA FLJ38443 fis, clone FEBRA2018433, highly similar to Rattus norvegicus glutamate receptor interacting protein 2 (GRIP2) mRNA. JD159115 - Sequence 140139 from Patent EP1572962. JD377954 - Sequence 358978 from Patent EP1572962. JD383359 - Sequence 364383 from Patent EP1572962. JD209384 - Sequence 190408 from Patent EP1572962. JD278233 - Sequence 259257 from Patent EP1572962. JD510873 - Sequence 491897 from Patent EP1572962. JD084966 - Sequence 65990 from Patent EP1572962. JD544259 - Sequence 525283 from Patent EP1572962. JD207250 - Sequence 188274 from Patent EP1572962. JD138991 - Sequence 120015 from Patent EP1572962. JD368764 - Sequence 349788 from Patent EP1572962. JD519801 - Sequence 500825 from Patent EP1572962. JD057047 - Sequence 38071 from Patent EP1572962. JD139478 - Sequence 120502 from Patent EP1572962. JD071534 - Sequence 52558 from Patent EP1572962. JD206462 - Sequence 187486 from Patent EP1572962.
Biochemical and Signaling Pathways
Reactome (by CSHL, EBI, and GO)
Protein Q9C0E4 (Reactome details) participates in the following event(s):
R-HSA-416985 Trafficking of GluR2-containing AMPA receptors to synapse R-HSA-421007 Endocytosis of Ca impermeable AMPA receptors R-HSA-416639 Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites R-HSA-416993 Trafficking of GluR2-containing AMPA receptors R-HSA-399719 Trafficking of AMPA receptors R-HSA-399721 Glutamate binding, activation of AMPA receptors and synaptic plasticity R-HSA-112314 Neurotransmitter receptors and postsynaptic signal transmission R-HSA-112315 Transmission across Chemical Synapses R-HSA-112316 Neuronal System