Human Gene CCDC13 (uc003cly.4)
  Description: Homo sapiens coiled-coil domain containing 13 (CCDC13), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr3:42,749,874-42,814,745 Size: 64,872 Total Exon Count: 16 Strand: -
Coding Region
   Position: hg19 chr3:42,750,472-42,799,837 Size: 49,366 Coding Exon Count: 15 

Page IndexSequence and LinksPrimersGenetic AssociationsCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr3:42,749,874-42,814,745)mRNA (may differ from genome)Protein (715 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCHPRDLynxMGI
neXtProtPubMedTreefamUniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): CCDC13
CDC HuGE Published Literature: CCDC13
Positive Disease Associations: Schizophrenia
Related Studies:
  1. Schizophrenia
    , , . [PubMed 0]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 6.10 RPKM in Testis
Total median expression: 26.50 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -29.7084-0.354 Picture PostScript Text
3' UTR -222.52598-0.372 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q8IYE1
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologGenome BrowserGenome BrowserNo orthologNo ortholog
Gene Details  Gene Details  
Gene Sorter  Gene Sorter  
  EnsemblFlyBase  
  Protein SequenceProtein Sequence  
  AlignmentAlignment  

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding

Biological Process:
GO:0006974 cellular response to DNA damage stimulus
GO:0030030 cell projection organization
GO:0031122 cytoplasmic microtubule organization
GO:1905515 non-motile cilium assembly

Cellular Component:
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0034451 centriolar satellite
GO:0042995 cell projection


-  Descriptions from all associated GenBank mRNAs
  BC036050 - Homo sapiens coiled-coil domain containing 13, mRNA (cDNA clone MGC:33372 IMAGE:5270468), complete cds.
KJ900289 - Synthetic construct Homo sapiens clone ccsbBroadEn_09683 CCDC13 gene, encodes complete protein.
AK058196 - Homo sapiens cDNA FLJ25467 fis, clone TST09387.
AK302859 - Homo sapiens cDNA FLJ61498 complete cds, highly similar to Coiled-coil domain-containing protein 13.

-  Other Names for This Gene
  Alternate Gene Symbols: CCD13_HUMAN, NM_144719, NP_653320, Q8IYE1
UCSC ID: uc003cly.4
RefSeq Accession: NM_144719
Protein: Q8IYE1 (aka CCD13_HUMAN)
CCDS: CCDS2705.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_144719.3
exon count: 16CDS single in 3' UTR: no RNA size: 2847
ORF size: 2148CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 3551.00frame shift in genome: no % Coverage: 99.40
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.