Human Gene C3orf18 (uc003dar.3)
Description: Homo sapiens chromosome 3 open reading frame 18 (C3orf18), transcript variant 1, mRNA.
Transcript (Including UTRs)
Position: hg19 chr3:50,595,456-50,605,223 Size: 9,768 Total Exon Count: 6 Strand: -
Coding Region
Position: hg19 chr3:50,597,088-50,603,130 Size: 6,043 Coding Exon Count: 4
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: CC018_HUMAN
DESCRIPTION: RecName: Full=Uncharacterized protein C3orf18; AltName: Full=Protein G20;
SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential).
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): C3orf18
CDC HuGE Published Literature: C3orf18
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q9UK00
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK124438 - Homo sapiens cDNA FLJ42447 fis, clone BRACE1000186, highly similar to Homo sapiens g20 protein.BC034766 - Homo sapiens chromosome 3 open reading frame 18, mRNA (cDNA clone MGC:34331 IMAGE:5177784), complete cds.AL833938 - Homo sapiens mRNA; cDNA DKFZp586G2119 (from clone DKFZp586G2119).AK130227 - Homo sapiens cDNA FLJ26717 fis, clone PNC03228.AF188706 - Homo sapiens g20 protein mRNA, complete cds.JD041182 - Sequence 22206 from Patent EP1572962.JD466918 - Sequence 447942 from Patent EP1572962.JD341274 - Sequence 322298 from Patent EP1572962.JD522215 - Sequence 503239 from Patent EP1572962.JD067963 - Sequence 48987 from Patent EP1572962.JD354134 - Sequence 335158 from Patent EP1572962.JD163321 - Sequence 144345 from Patent EP1572962.JD424192 - Sequence 405216 from Patent EP1572962.JD105195 - Sequence 86219 from Patent EP1572962.JD270437 - Sequence 251461 from Patent EP1572962.JD126203 - Sequence 107227 from Patent EP1572962.JD475492 - Sequence 456516 from Patent EP1572962.JD185820 - Sequence 166844 from Patent EP1572962.JD409749 - Sequence 390773 from Patent EP1572962.JD318283 - Sequence 299307 from Patent EP1572962.JD351110 - Sequence 332134 from Patent EP1572962.JD260417 - Sequence 241441 from Patent EP1572962.JD287535 - Sequence 268559 from Patent EP1572962.JD259223 - Sequence 240247 from Patent EP1572962.JD108388 - Sequence 89412 from Patent EP1572962.JD422969 - Sequence 403993 from Patent EP1572962.JD111118 - Sequence 92142 from Patent EP1572962.JD119709 - Sequence 100733 from Patent EP1572962.AK308074 - Homo sapiens cDNA, FLJ98022.JD408318 - Sequence 389342 from Patent EP1572962.JD437316 - Sequence 418340 from Patent EP1572962.JD277210 - Sequence 258234 from Patent EP1572962.JD341335 - Sequence 322359 from Patent EP1572962.JD040885 - Sequence 21909 from Patent EP1572962.JD486588 - Sequence 467612 from Patent EP1572962.JD171706 - Sequence 152730 from Patent EP1572962.JD083861 - Sequence 64885 from Patent EP1572962.AK311093 - Homo sapiens cDNA, FLJ18135.JD540729 - Sequence 521753 from Patent EP1572962.AK309486 - Homo sapiens cDNA, FLJ99527.JD125025 - Sequence 106049 from Patent EP1572962.JD111531 - Sequence 92555 from Patent EP1572962.JD133133 - Sequence 114157 from Patent EP1572962.JD443667 - Sequence 424691 from Patent EP1572962.JD439061 - Sequence 420085 from Patent EP1572962.JD465815 - Sequence 446839 from Patent EP1572962.JD289985 - Sequence 271009 from Patent EP1572962.JD519636 - Sequence 500660 from Patent EP1572962.JD416712 - Sequence 397736 from Patent EP1572962.JD368613 - Sequence 349637 from Patent EP1572962.AK313128 - Homo sapiens cDNA, FLJ93615, Homo sapiens g20 protein (LOC51161), mRNA.CU689966 - Synthetic construct Homo sapiens gateway clone IMAGE:100020620 5' read C3orf18 mRNA.HQ448381 - Synthetic construct Homo sapiens clone IMAGE:100071806; CCSB009343_02 chromosome 3 open reading frame 18 (C3orf18) gene, encodes complete protein.KJ898841 - Synthetic construct Homo sapiens clone ccsbBroadEn_08235 C3orf18 gene, encodes complete protein.JD203278 - Sequence 184302 from Patent EP1572962.JD510258 - Sequence 491282 from Patent EP1572962.JD552940 - Sequence 533964 from Patent EP1572962.JD416913 - Sequence 397937 from Patent EP1572962.JD083871 - Sequence 64895 from Patent EP1572962.JD365342 - Sequence 346366 from Patent EP1572962.JD117448 - Sequence 98472 from Patent EP1572962.JD222209 - Sequence 203233 from Patent EP1572962.JD144471 - Sequence 125495 from Patent EP1572962.JD076324 - Sequence 57348 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: CC018_HUMAN, NM_016210, NP_057294, Q9UK00UCSC ID: uc003dar.3RefSeq Accession: NM_016210
Protein: Q9UK00
(aka CC018_HUMAN)
CCDS: CCDS2829.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_016210.4
exon count:
6 CDS single in 3' UTR:
no
RNA size:
2712
ORF size:
489 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
1023.00 frame shift in genome:
no
% Coverage:
99.63
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.