Human Gene CFAP44 (uc003eae.2)
Description: Homo sapiens WD repeat domain 52 (CFAP44), transcript variant 2, mRNA.Transcript (Including UTRs) Position: hg19 chr3:113,081,712-113,160,361 Size: 78,650 Total Exon Count: 21 Strand: -Coding Region Position: hg19 chr3:113,081,977-113,152,511 Size: 70,535 Coding Exon Count: 20
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: WDR52_HUMAN DESCRIPTION: RecName: Full=WD repeat-containing protein 52;SIMILARITY: Contains 9 WD repeats.
Primer design for this transcript
MalaCards Disease Associations
Common Gene Haplotype Alleles
Press "+" in the title bar above to open this section.
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
Press "+" in the title bar above to open this section.
mRNA Secondary Structure of 3' and 5' UTRs
Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR015943 - WD40/YVTN_repeat-like_domIPR001680 - WD40_repeatIPR019775 - WD40_repeat_CSIPR017986 - WD40_repeat_domPfam Domains: PF00400 - WD domain, G-beta repeatSCOP Domains: 50952 - Soluble quinoprotein glucose dehydrogenase50960 - TolB, C-terminal domain63829 - Calcium-dependent phosphotriesterase69304 - Tricorn protease N-terminal domain101898 - NHL repeat50965 - Galactose oxidase, central domain75011 - 3-carboxy-cis,cis-mucoante lactonizing enzyme101908 - Putative isomerase YbhE50969 - YVTN repeat-like/Quinoprotein amine dehydrogenase50974 - Nitrous oxide reductase, N-terminal domain50978 - WD40 repeat-like50993 - Prolyl oligopeptidase, N-terminal domain69322 - Tricorn protease domain 250998 - Quinoprotein alcohol dehydrogenase-like51004 - C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase82171 - Dipeptidyl peptidase IV/CD26, N-terminal domainModBase Predicted Comparative 3D Structure on Q96MT7 The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog Gene Details Gene Sorter
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
AK056472 - Homo sapiens cDNA FLJ31910 fis, clone NT2RP7004687, weakly similar to VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1.BC101582 - Homo sapiens WD repeat domain 52, mRNA (cDNA clone MGC:126631 IMAGE:8069088), complete cds.BC113553 - Homo sapiens WD repeat domain 52, mRNA (cDNA clone MGC:142113 IMAGE:8322605), complete cds.AL133606 - Homo sapiens mRNA; cDNA DKFZp434A2017 (from clone DKFZp434A2017).JD168657 - Sequence 149681 from Patent EP1572962.JD359376 - Sequence 340400 from Patent EP1572962.JD057485 - Sequence 38509 from Patent EP1572962.
Other Names for This Gene
Alternate Gene Symbols: NM_018338, NP_060808, Q96MT7, WDR52, WDR52_HUMANUCSC ID: uc003eae.2RefSeq Accession: NM_018338 Protein: Q96MT7
(aka WDR52_HUMAN)CCDS: CCDS2972.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_018338.3
exon count:
21 CDS single in 3' UTR:
no
RNA size:
3281 ORF size:
2949 CDS single in intron:
no
Alignment % ID:
100.00 txCdsPredict score:
5984.00 frame shift in genome:
no
% Coverage:
100.00 has start codon:
yes
stop codon in genome:
no
# of Alignments:
1 has end codon:
yes
retained intron:
no
# AT/AC introns
0 selenocysteine:
no
end bleed into intron:
280 # strange splices:
0
Click here
for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
Click here
for details on how this gene model was made and data restrictions if any.
US Server
