Human Gene NSUN7 (uc003gvh.2)
  Description: Homo sapiens NOP2/Sun domain family, member 7 (NSUN7), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr4:40,751,914-40,777,473 Size: 25,560 Total Exon Count: 6 Strand: +
Coding Region
   Position: hg19 chr4:40,752,711-40,776,976 Size: 24,266 Coding Exon Count: 5 

Page IndexSequence and LinksPrimersCTDGene AllelesRNA-Seq Expression
Microarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther Names
Model InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:40,751,914-40,777,473)mRNA (may differ from genome)Protein (277 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVHGNCLynxMGIOMIMPubMed
UniProtKBBioGrid CRISPR DB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 11.85 RPKM in Testis
Total median expression: 78.37 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -225.00495-0.455 Picture PostScript Text
3' UTR -115.22497-0.232 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q8NE18-3
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
 Protein Sequence    
 Alignment    

-  Descriptions from all associated GenBank mRNAs
  BC042401 - Homo sapiens NOL1/NOP2/Sun domain family, member 7, mRNA (cDNA clone IMAGE:5168018).
BC036568 - Homo sapiens NOL1/NOP2/Sun domain family, member 7, mRNA (cDNA clone MGC:41781 IMAGE:5272990), complete cds.
AK024063 - Homo sapiens cDNA FLJ14001 fis, clone Y79AA1002298.
AK304048 - Homo sapiens cDNA FLJ61535 complete cds.
CU691376 - Synthetic construct Homo sapiens gateway clone IMAGE:100020906 5' read NSUN7 mRNA.
HQ448035 - Synthetic construct Homo sapiens clone IMAGE:100071410; CCSB010511_02 NOL1/NOP2/Sun domain family, member 7 (NSUN7) gene, encodes complete protein.
KJ903210 - Synthetic construct Homo sapiens clone ccsbBroadEn_12604 NSUN7 gene, encodes complete protein.
JD489849 - Sequence 470873 from Patent EP1572962.
JD060050 - Sequence 41074 from Patent EP1572962.
JD202097 - Sequence 183121 from Patent EP1572962.
JD443848 - Sequence 424872 from Patent EP1572962.
JD255167 - Sequence 236191 from Patent EP1572962.
JD537769 - Sequence 518793 from Patent EP1572962.
JD328862 - Sequence 309886 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AK024063, NM_024677, NP_078953, Q8NE18-3
UCSC ID: uc003gvh.2
RefSeq Accession: NM_024677
Protein: Q8NE18-3, splice isoform of Q8NE18

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: AK024063.1
exon count: 6CDS single in 3' UTR: no RNA size: 1759
ORF size: 834CDS single in intron: no Alignment % ID: 99.83
txCdsPredict score: 1754.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 506# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.