Human Gene MTHFD2L (uc003hhs.2)
  Description: Homo sapiens methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like (MTHFD2L), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr4:75,023,829-75,049,528 Size: 25,700 Total Exon Count: 7 Strand: +


Page IndexSequence and LinksPrimersGenetic AssociationsCTDRNA-Seq Expression
Microarray ExpressionOther SpeciesmRNA DescriptionsPathwaysOther NamesModel Information
Methods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:75,023,829-75,049,528)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTATable SchemaBioGPSEnsembl
ExonPrimerH-INVHGNCLynxPubMedWikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): MTHFD2L
CDC HuGE Published Literature: MTHFD2L

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 2.78 RPKM in Thyroid
Total median expression: 75.70 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC032771 - Homo sapiens methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like, mRNA (cDNA clone IMAGE:3885359), complete cds.
KJ904300 - Synthetic construct Homo sapiens clone ccsbBroadEn_13694 MTHFD2L gene, encodes complete protein.
CU689528 - Synthetic construct Homo sapiens gateway clone IMAGE:100017927 5' read MTHFD2L mRNA.
AX794781 - Sequence 8 from Patent WO03052093.
AX794785 - Sequence 12 from Patent WO03052093.
AX794782 - Sequence 9 from Patent WO03052093.
BC037529 - Homo sapiens methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like, mRNA (cDNA clone IMAGE:4794959), complete cds.
BC041943 - Homo sapiens methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like, mRNA (cDNA clone IMAGE:5301277).
AX794779 - Sequence 6 from Patent WO03052093.
JD187475 - Sequence 168499 from Patent EP1572962.
JD339077 - Sequence 320101 from Patent EP1572962.
JD236847 - Sequence 217871 from Patent EP1572962.
JD267309 - Sequence 248333 from Patent EP1572962.
AK021544 - Homo sapiens cDNA FLJ11482 fis, clone HEMBA1001820.
JD096372 - Sequence 77396 from Patent EP1572962.
JD308832 - Sequence 289856 from Patent EP1572962.
JD332023 - Sequence 313047 from Patent EP1572962.

-  Biochemical and Signaling Pathways
  KEGG - Kyoto Encyclopedia of Genes and Genomes
hsa00630 - Glyoxylate and dicarboxylate metabolism
hsa00670 - One carbon pool by folate
hsa01100 - Metabolic pathways

-  Other Names for This Gene
  Alternate Gene Symbols: BC037529
UCSC ID: uc003hhs.2
RefSeq Accession: NM_001144978

-  Gene Model Information
 
category: nearCoding nonsense-mediated-decay: no RNA accession: BC037529.2
exon count: 7CDS single in 3' UTR: no RNA size: 2072
ORF size: 0CDS single in intron: no Alignment % ID: 99.75
txCdsPredict score: 234.00frame shift in genome: no % Coverage: 90.88
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.