Human Gene ART3 (uc003hjq.3)
  Description: Homo sapiens ADP-ribosyltransferase 3 (ART3), transcript variant 3, mRNA.
RefSeq Summary (NM_001130017): This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011].
Transcript (Including UTRs)
   Position: hg19 chr4:76,997,034-77,033,955 Size: 36,922 Total Exon Count: 5 Strand: +


Page IndexSequence and LinksPrimersGenetic AssociationsCTDRNA-Seq Expression
Microarray ExpressionOther SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr4:76,997,034-77,033,955)mRNA (may differ from genome)No protein
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
BioGPSEnsemblExonPrimerGeneNetworkH-INVHGNC
LynxPubMedTreefamWikipedia

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Genetic Association Studies of Complex Diseases and Disorders
  Genetic Association Database (archive): ART3
CDC HuGE Published Literature: ART3
Positive Disease Associations: Albumins
Related Studies:
  1. Albumins
    , , . [PubMed 0]

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 44.30 RPKM in Muscle - Skeletal
Total median expression: 183.27 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AK225860 - Homo sapiens mRNA for Splice isoform 1 of Q13508 variant, clone: FCC125B01.
AY543657 - Homo sapiens clone MF 15.3 mono-ADP-ribosyltransferase (ART3) mRNA, 5' UTR and partial cds.
AY543658 - Homo sapiens clone MF 17.12 mono-ADP-ribosyltransferase (ART3) mRNA, 5' UTR and partial cds.
AY543659 - Homo sapiens clone MF 18.8 mono-ADP-ribosyltransferase (ART3) mRNA, 5' UTR and partial cds.
AY543656 - Homo sapiens clone MF(IR) 1.3 mono-ADP-ribosyltransferase (ART3) mRNA, 5' UTR and partial cds.
U47054 - Human putative mono-ADP-ribosyltransferase (htMART) mRNA, complete cds.
AY543660 - Homo sapiens clone MF 16.5 mono-ADP-ribosyltransferase (ART3) mRNA, 5' UTR and partial cds.
BC008397 - Homo sapiens ADP-ribosyltransferase 3, mRNA (cDNA clone MGC:14489 IMAGE:4244549), complete cds.
BC017913 - Homo sapiens ADP-ribosyltransferase 3, mRNA (cDNA clone MGC:23844 IMAGE:4292261), complete cds.
AK295305 - Homo sapiens cDNA FLJ60045 complete cds, highly similar to Ecto-ADP-ribosyltransferase 3 precursor (EC 2.4.2.31).
AK308810 - Homo sapiens cDNA, FLJ98851.
AY543655 - Homo sapiens clone MF(IR) 50.19 mono-ADP-ribosyltransferase (ART3) mRNA, 5' UTR and partial cds.
AY550336 - Homo sapiens mono-ADP-ribosyltransferase 3 variant II mRNA, complete cds, alternatively spliced.
AY550337 - Homo sapiens mono-ADP-ribosyltransferase 3 variant III mRNA, complete cds, alternatively spliced.
AY550338 - Homo sapiens mono-ADP-ribosyltransferase 3 mRNA, complete cds, alternatively spliced.
CU676112 - Synthetic construct Homo sapiens gateway clone IMAGE:100022251 5' read ART3 mRNA.
DQ896614 - Synthetic construct Homo sapiens clone IMAGE:100011074; FLH195926.01L; RZPDo839H10151D ADP-ribosyltransferase 3 (ART3) gene, encodes complete protein.
KJ890714 - Synthetic construct Homo sapiens clone ccsbBroadEn_00108 ART3 gene, encodes complete protein.
KJ896460 - Synthetic construct Homo sapiens clone ccsbBroadEn_05854 ART3 gene, encodes complete protein.
BT007249 - Homo sapiens ADP-ribosyltransferase 3 mRNA, complete cds.
CR541664 - Homo sapiens full open reading frame cDNA clone RZPDo834H0227D for gene ART3, ADP-ribosyltransferase 3; complete cds, incl. stopcodon.
DQ893283 - Synthetic construct clone IMAGE:100005913; FLH195930.01X; RZPDo839H10152D ADP-ribosyltransferase 3 (ART3) gene, encodes complete protein.
AY550341 - Homo sapiens mono-ADP-ribosyltransferase 3 variant Ia mRNA, partial cds, alternatively spliced.
AY550342 - Homo sapiens mono-ADP-ribosyltransferase 3 variant Ib mRNA, partial cds, alternatively spliced.
AY550343 - Homo sapiens mono-ADP-ribosyltransferase 3 variant Ic1 mRNA, partial cds, alternatively spliced.
AY550344 - Homo sapiens mono-ADP-ribosyltransferase 3 variant Ic2 mRNA, partial cds, alternatively spliced.
AY550345 - Homo sapiens mono-ADP-ribosyltransferase 3 variant Ic3 mRNA, partial cds, alternatively spliced.
AY550346 - Homo sapiens mono-ADP-ribosyltransferase 3 variant Id mRNA, partial cds, alternatively spliced.
AY550339 - Homo sapiens mono-ADP-ribosyltransferase 3 mRNA, partial cds, alternatively spliced.
AY550340 - Homo sapiens mono-ADP-ribosyltransferase 3 mRNA, partial cds, alternatively spliced.
JD314839 - Sequence 295863 from Patent EP1572962.
JD168015 - Sequence 149039 from Patent EP1572962.
JD350254 - Sequence 331278 from Patent EP1572962.
JD089998 - Sequence 71022 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: AY550338
UCSC ID: uc003hjq.3
RefSeq Accession: NM_001130017

-  Gene Model Information
 
category: nearCoding nonsense-mediated-decay: no RNA accession: AY550338.1
exon count: 5CDS single in 3' UTR: no RNA size: 323
ORF size: 0CDS single in intron: no Alignment % ID: 99.69
txCdsPredict score: 440.00frame shift in genome: no % Coverage: 100.00
has start codon: no stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.