Description: Homo sapiens WW and C2 domain containing 1 (WWC1), transcript variant 2, mRNA. RefSeq Summary (NM_001161662): The protein encoded by this gene is a cytoplasmic phosphoprotein that interacts with PRKC-zeta and dynein light chain-1. Alleles of this gene have been found that enhance memory in some individuals. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]. Transcript (Including UTRs) Position: hg19 chr5:167,719,065-167,899,308 Size: 180,244 Total Exon Count: 23 Strand: + Coding Region Position: hg19 chr5:167,719,158-167,896,022 Size: 176,865 Coding Exon Count: 23
ID:H3BLZ3_HUMAN DESCRIPTION: SubName: Full=Protein KIBRA; Flags: Fragment; SIMILARITY: Contains 1 C2 domain. CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
memory disturbance Schaper, K. et al. 2007, KIBRA gene variants are associated with episodic memory in healthy elderly, Neurobiol Aging 2007.
[PubMed 17353070]
monocyte chemoattractant protein 1 (66-77) , , .
[PubMed 0]
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on H3BLZ3
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.