The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
ModBase Predicted Comparative 3D Structure on Q6NTE8
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Biological Process: GO:0006281 DNA repair GO:0006974 cellular response to DNA damage stimulus GO:0007095 mitotic G2 DNA damage checkpoint GO:0010212 response to ionizing radiation GO:0045860 positive regulation of protein kinase activity GO:0071168 protein localization to chromatin GO:1905168 positive regulation of double-strand break repair via homologous recombination GO:2001032 regulation of double-strand break repair via nonhomologous end joining