Human Gene MYB (uc003qfj.3)
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Sequence and Links to Tools and Databases
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Primer design for this transcript
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Genetic Association Studies of Complex Diseases and Disorders
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Genetic Association Database (archive): MYB
CDC HuGE Published Literature: MYB
Positive Disease Associations: Beta thalassemia/hemoglobin E disease
, hematocrit
, hematological parameters
, mean corpuscular hemoglobin
, mean corpuscular volume
, other erythrocyte phenotypes
Related Studies: - Beta thalassemia/hemoglobin E disease
Nuinoon ,et al. 2009, A genome-wide association identified the common genetic variants influence disease severity in beta(0)-thalassemia/hemoglobin E, Human genetics 2009 .
[PubMed 19924444]
- hematocrit
Ganesh ,et al. 2009, Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium, Nature genetics 2009 41- 11 : 1191-8.
[PubMed 19862010]
- hematological parameters
Soranzo ,et al. 2009, A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium, Nature genetics 2009 41- 11 : 1182-90.
[PubMed 19820697]
  more ... click here to view the complete list
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MalaCards Disease Associations
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MalaCards Gene Search: MYB
Diseases sorted by gene-association score: angiocentric glioma* (260), acute basophilic leukemia* (247), precursor t-cell acute lymphoblastic leukemia* (106), leukemia, acute lymphoblastic* (30), tuberculous salpingitis (15), malignant histiocytosis (12), trachea adenoid cystic carcinoma (10), gallbladder adenocarcinoma (10), tracheal cancer (7), bone ewing's sarcoma (6), myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency (5), polymorphous low-grade adenocarcinoma (5), leukemia, chronic myeloid, somatic (2), leukemia, acute myeloid (0) * = Manually curated disease association
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Comparative Toxicogenomics Database (CTD)
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
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Microarray Expression Data
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Press "+" in the title bar above to open this section.
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Orthologous Genes in Other Species
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Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse | Rat | Zebrafish | D. melanogaster | C. elegans | S. cerevisiae |
No ortholog | No ortholog | No ortholog | No ortholog | No ortholog | No ortholog |
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Descriptions from all associated GenBank mRNAs
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AJ606317 - Homo sapiens mRNA for v-myb myeloblastosis viral oncogene homologue (avian), (c-myb gene), splice variant 8A. AJ606318 - Homo sapiens mRNA for v-myb myeloblastosis viral oncogene homologue (avian), (c-myb gene), splice variant 9Ai. AJ606319 - Homo sapiens mRNA for v-myb myeloblastosis viral oncogene homologue (avian), (c-myb gene), splice variant 9Aii. AJ606320 - Homo sapiens mRNA for v-myb myeloblastosis viral oncogene homologue (avian), (c-myb gene), splice variant 8. AJ606321 - Homo sapiens mRNA for v-myb myeloblastosis viral oncogene homologue (avian), (c-myb gene), splice variant 8B. AJ606322 - Homo sapiens mRNA for v-myb myeloblastosis viral oncogene homologue (avian), (c-myb gene), splice variant 10A. AJ606323 - Homo sapiens mRNA for v-myb myeloblastosis viral oncogene homologue (avian), (c-myb gene), splice variant 13A. AJ606324 - Homo sapiens mRNA for v-myb myeloblastosis viral oncogene homologue (avian), (c-myb gene), splice variant 14A. FW340095 - Screening. X52125 - Human alternatively spliced c-myb mRNA (clone=pMbm-1). BC064955 - Homo sapiens v-myb myeloblastosis viral oncogene homolog (avian), mRNA (cDNA clone MGC:70781 IMAGE:6069320), complete cds. AJ616235 - Homo sapiens mRNA for v-myb myeloblastosis viral oncogene homologue (avian), (c-myb gene). M15024 - Human c-myb mRNA, complete cds. AF104863 - Homo sapiens MYB proto-oncogene protein (MYB) mRNA, complete cds. AB527731 - Synthetic construct DNA, clone: pF1KB6253, Homo sapiens MYB gene for v-myb myeloblastosis viral oncogene homolog, without stop codon, in Flexi system. KJ891658 - Synthetic construct Homo sapiens clone ccsbBroadEn_01052 MYB gene, encodes complete protein. AY787443 - Homo sapiens isolate DelE13 c-myb-like mRNA, complete sequence. AY787444 - Homo sapiens isolate DelE3E5 c-myb-like mRNA, complete sequence. AY787445 - Homo sapiens isolate DelE3E8A c-myb-like mRNA, complete sequence. AY787446 - Homo sapiens isolate DelE5E8A c-myb-like mRNA, complete sequence. AY787447 - Homo sapiens isolate DelE8 c-myb-like mRNA, complete sequence. AY787448 - Homo sapiens isolate DelE9 c-myb-like mRNA, complete sequence. AY787452 - Homo sapiens isolate E12L-2 c-myb-like mRNA, complete sequence. AY787453 - Homo sapiens isolate E13A c-myb-like mRNA, complete sequence. AY787454 - Homo sapiens isolate E8A c-myb-like mRNA, complete sequence. AY787455 - Homo sapiens isolate E8A2E9B c-myb-like mRNA, complete sequence. AY787459 - Homo sapiens isolate E8SE8A c-myb-like mRNA, complete sequence. AY787460 - Homo sapiens isolate E8SE8AE9B c-myb-like mRNA, complete sequence. AY787461 - Homo sapiens isolate E8SE9B c-myb-like mRNA, complete sequence. AY787462 - Homo sapiens isolate E8SE9S-85E9AB c-myb-like mRNA, complete sequence. AY787463 - Homo sapiens isolate E8SE9S-85E9B c-myb-like mRNA, complete sequence. AY787464 - Homo sapiens isolate E9A c-myb-like mRNA, complete sequence. AY787465 - Homo sapiens isolate E9AB c-myb-like mRNA, complete sequence. AY787467 - Homo sapiens isolate E9B c-myb-like mRNA, complete sequence. AY787468 - Homo sapiens isolate E9S-48E9B c-myb-like mRNA, complete sequence. AY787470 - Homo sapiens isolate E9S-85 c-myb-like mRNA, complete sequence. AY787472 - Homo sapiens isolate E9S-85E9A c-myb-like mRNA, complete sequence. AY787473 - Homo sapiens isolate E9S-85E9AB c-myb-like mRNA, complete sequence. AY787474 - Homo sapiens isolate E9S-85E9B c-myb-like mRNA, complete sequence. AY787475 - Homo sapiens isolate M15024 c-myb-like mRNA, complete sequence. AY787451 - Homo sapiens isolate E12L-1 c-myb-like mRNA, complete sequence. AY787449 - Homo sapiens isolate DelE9E10A c-myb-like mRNA, complete sequence. AY787450 - Homo sapiens isolate E10A c-myb-like mRNA, complete sequence. AY787456 - Homo sapiens isolate E8AE10A.txt c-myb-like mRNA, complete sequence. AY787457 - Homo sapiens isolate E8AE9S-85E10A c-myb-like mRNA, complete sequence. AY787458 - Homo sapiens isolate E8SE10A c-myb-like mRNA, complete sequence. AY787466 - Homo sapiens isolate E9AE10A c-myb-like mRNA, complete sequence. AY787469 - Homo sapiens isolate E9S-48E9BE10A c-myb-like mRNA, complete sequence. AY787471 - Homo sapiens isolate E9S-85E10A c-myb-like mRNA, complete sequence. X52126 - Human alternatively spliced c-myb mRNA (clone=pMbm-2). M13665 - Human c-myb mRNA, 3'end. BC035996 - Homo sapiens, Similar to v-myb myeloblastosis viral oncogene homolog (avian), clone IMAGE:4686589, mRNA. AJ616791 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 1 and joined CDS. JD445418 - Sequence 426442 from Patent EP1572962. JD173383 - Sequence 154407 from Patent EP1572962. JD057050 - Sequence 38074 from Patent EP1572962. AJ616792 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 2. M13666 - Human c-myb mRNA, 3' end. AJ616793 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 3. AJ616794 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 4. FJ969915 - Homo sapiens MYB/NFIB fusion protein variant 1 (MYB/NFIB fusion) mRNA, partial cds. FJ969916 - Homo sapiens MYB/NFIB fusion protein variant 2 (MYB/NFIB fusion) mRNA, partial cds. FJ969917 - Homo sapiens MYB/NFIB fusion protein variant 3 (MYB/NFIB fusion) mRNA, partial cds. AJ616795 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 5. AJ616796 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 6. AJ616797 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 7. AJ616798 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 8. X17469 - Human mRNA for c-myb gene exon 9A. AJ616800 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 10. AJ616801 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 11. AJ616802 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 12. CQ873766 - Sequence 185 from Patent WO2004076622. DD413603 - Regulation of Mammalian Cells. AJ616803 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 13. AJ616804 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 14. AJ616805 - Homo sapiens c-myb gene for v-myb myeloblastosis viral oncogene homologue (avian), exon 15. JD545763 - Sequence 526787 from Patent EP1572962. JD333991 - Sequence 315015 from Patent EP1572962. FW573307 - JP 2010529847-A/28: Oligonucleotides for modulation of target RNA activity. HI463868 - Sequence 13 from Patent EP2124967. JD557793 - Sequence 538817 from Patent EP1572962. CQ873705 - Sequence 124 from Patent WO2004076622. DD413542 - Regulation of Mammalian Cells. HI463869 - Sequence 14 from Patent EP2124967. HI463870 - Sequence 15 from Patent EP2124967. FW573305 - JP 2010529847-A/26: Oligonucleotides for modulation of target RNA activity. FW573306 - JP 2010529847-A/27: Oligonucleotides for modulation of target RNA activity. HI463871 - Sequence 16 from Patent EP2124967. HI463872 - Sequence 17 from Patent EP2124967. FW573308 - JP 2010529847-A/29: Oligonucleotides for modulation of target RNA activity. HI463873 - Sequence 18 from Patent EP2124967. HI463874 - Sequence 19 from Patent EP2124967. HI463875 - Sequence 20 from Patent EP2124967. JD232050 - Sequence 213074 from Patent EP1572962. HI463876 - Sequence 21 from Patent EP2124967. HI463877 - Sequence 22 from Patent EP2124967. JD182305 - Sequence 163329 from Patent EP1572962.
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Other Names for This Gene
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Alternate Gene Symbols: AY787449 UCSC ID: uc003qfj.3 RefSeq Accession: NM_001161657
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Gene Model Information
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category:
| nearCoding
| nonsense-mediated-decay:
| yes
| RNA accession:
| AY787449.1
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exon count:
| 15 | CDS single in 3' UTR:
| no
| RNA size:
| 2911 |
ORF size:
| 0 | CDS single in intron:
| no
| Alignment % ID:
| 100.00 |
txCdsPredict score:
| 1967.00 | frame shift in genome:
| no
| % Coverage:
| 100.00 |
has start codon:
| yes
| stop codon in genome:
| no
| # of Alignments:
| 1 |
has end codon:
| yes
| retained intron:
| no
| # AT/AC introns
| 0 |
selenocysteine:
| no
| end bleed into intron:
| 0 | # strange splices:
| 0 |
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Click here
for a detailed description of the fields of the table above.
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Methods, Credits, and Use Restrictions
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Click here
for details on how this gene model was made and data restrictions if any.
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