Human Gene RSPH10B (uc003spg.1)
  Description: Homo sapiens radial spoke head 10 homolog B (Chlamydomonas) (RSPH10B), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr7:5,965,777-6,000,495 Size: 34,719 Total Exon Count: 17 Strand: -
Coding Region
   Position: hg19 chr7:5,966,175-6,000,435 Size: 34,261 Coding Exon Count: 17 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:5,965,777-6,000,495)mRNA (may differ from genome)Protein (613 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblExonPrimerGeneCardsGeneNetworkH-INV
HGNCLynxMGIneXtProtPubMedTreefam
UniProtKBWikipedia

-  Comments and Description Text from UniProtKB
  ID: R10B1_HUMAN
DESCRIPTION: RecName: Full=Radial spoke head 10 homolog B;
SIMILARITY: Contains 10 MORN repeats.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 6.90 RPKM in Testis
Total median expression: 10.12 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
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-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -12.9060-0.215 Picture PostScript Text
3' UTR -117.12398-0.294 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR003409 - MORN

Pfam Domains:
PF02493 - MORN repeat

SCOP Domains:
82185 - Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain

ModBase Predicted Comparative 3D Structure on P0C881
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The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  BC044242 - Homo sapiens radial spoke head 10 homolog B2 (Chlamydomonas), mRNA (cDNA clone IMAGE:5753714), complete cds.
BC034495 - Homo sapiens radial spoke head 10 homolog B (Chlamydomonas), mRNA (cDNA clone MGC:26728 IMAGE:4825868), complete cds.
JD054963 - Sequence 35987 from Patent EP1572962.
JD051896 - Sequence 32920 from Patent EP1572962.
AK093411 - Homo sapiens cDNA FLJ36092 fis, clone TESTI2020525, weakly similar to Phosphatidylinositol-4-phosphate 5-kinase homolog T3K9.2.
AX748110 - Sequence 1635 from Patent EP1308459.
JD452434 - Sequence 433458 from Patent EP1572962.
BC157864 - Homo sapiens radial spoke head 10 homolog B (Chlamydomonas), mRNA (cDNA clone MGC:189759 IMAGE:9057083), complete cds.
BC157871 - Homo sapiens radial spoke head 10 homolog B (Chlamydomonas), mRNA (cDNA clone MGC:189766 IMAGE:9057090), complete cds.
AK314983 - Homo sapiens cDNA, FLJ95901.
KJ904047 - Synthetic construct Homo sapiens clone ccsbBroadEn_13441 RSPH10B gene, encodes complete protein.
AK294481 - Homo sapiens cDNA FLJ54347 complete cds.
KJ904345 - Synthetic construct Homo sapiens clone ccsbBroadEn_13739 RSPH10B2 gene, encodes complete protein.
CU692192 - Synthetic construct Homo sapiens gateway clone IMAGE:100021340 5' read RSPH10B mRNA.
CU689906 - Synthetic construct Homo sapiens gateway clone IMAGE:100020419 5' read RSPH10B mRNA.

-  Other Names for This Gene
  Alternate Gene Symbols: A6NMW7, AX748110, P0C881, Q86ST9, Q8NE68, R10B1_HUMAN
UCSC ID: uc003spg.1
RefSeq Accession: NM_173565
Protein: P0C881 (aka R10B1_HUMAN)

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: AX748110.1
exon count: 17CDS single in 3' UTR: no RNA size: 2161
ORF size: 1842CDS single in intron: no Alignment % ID: 99.81
txCdsPredict score: 2606.00frame shift in genome: no % Coverage: 99.68
has start codon: yes stop codon in genome: no # of Alignments: 2
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.