Human Gene ZC3HAV1L (uc003vum.1)
  Description: Homo sapiens zinc finger CCCH-type, antiviral 1-like (ZC3HAV1L), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr7:138,710,452-138,720,775 Size: 10,324 Total Exon Count: 5 Strand: -
Coding Region
   Position: hg19 chr7:138,711,290-138,720,763 Size: 9,474 Coding Exon Count: 5 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
RNA-Seq ExpressionMicroarray ExpressionRNA StructureProtein StructureOther SpeciesGO Annotations
mRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:138,710,452-138,720,775)mRNA (may differ from genome)Protein (300 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneGene interactionsTable Schema
AlphaFoldBioGPSEnsemblEntrez GeneExonPrimerGeneCards
GeneNetworkH-INVHGNCHPRDLynxMGI
neXtProtPubMedTreefamUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: ZCCHL_HUMAN
DESCRIPTION: RecName: Full=Zinc finger CCCH-type antiviral protein 1-like;
PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.
CAUTION: Despite its name, it does not contain a canonical C3H1- type zinc-finger.

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 6.31 RPKM in Cells - EBV-transformed lymphocytes
Total median expression: 82.81 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
3' UTR -247.50838-0.295 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR026693 - Zc3hav1_like

ModBase Predicted Comparative 3D Structure on Q96H79
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0005829 cytosol


-  Descriptions from all associated GenBank mRNAs
  BC020784 - Homo sapiens zinc finger CCCH-type, antiviral 1-like, mRNA (cDNA clone IMAGE:4773508), complete cds.
HQ257901 - Synthetic construct Homo sapiens clone IMAGE:100072210 Unknown protein gene, encodes complete protein.
BC008842 - Homo sapiens zinc finger CCCH-type, antiviral 1-like, mRNA (cDNA clone MGC:14289 IMAGE:4136104), complete cds.
LF384093 - JP 2014500723-A/191596: Polycomb-Associated Non-Coding RNAs.
JD349631 - Sequence 330655 from Patent EP1572962.
JD064309 - Sequence 45333 from Patent EP1572962.
JD295441 - Sequence 276465 from Patent EP1572962.
JD072020 - Sequence 53044 from Patent EP1572962.
JD425918 - Sequence 406942 from Patent EP1572962.
JD255809 - Sequence 236833 from Patent EP1572962.
JD212264 - Sequence 193288 from Patent EP1572962.
JD195475 - Sequence 176499 from Patent EP1572962.
JD463282 - Sequence 444306 from Patent EP1572962.
JD071444 - Sequence 52468 from Patent EP1572962.
JD535553 - Sequence 516577 from Patent EP1572962.
JD035116 - Sequence 16140 from Patent EP1572962.
JD152351 - Sequence 133375 from Patent EP1572962.
JD258829 - Sequence 239853 from Patent EP1572962.
JD293365 - Sequence 274389 from Patent EP1572962.
JD515278 - Sequence 496302 from Patent EP1572962.
JD496306 - Sequence 477330 from Patent EP1572962.
JD187566 - Sequence 168590 from Patent EP1572962.
JD146915 - Sequence 127939 from Patent EP1572962.
JD538774 - Sequence 519798 from Patent EP1572962.
JD423448 - Sequence 404472 from Patent EP1572962.
JD187655 - Sequence 168679 from Patent EP1572962.
JD482381 - Sequence 463405 from Patent EP1572962.
JD220684 - Sequence 201708 from Patent EP1572962.
JD202604 - Sequence 183628 from Patent EP1572962.
JD538955 - Sequence 519979 from Patent EP1572962.
JD548613 - Sequence 529637 from Patent EP1572962.
LF213027 - JP 2014500723-A/20530: Polycomb-Associated Non-Coding RNAs.
LF361745 - JP 2014500723-A/169248: Polycomb-Associated Non-Coding RNAs.
JD020167 - Sequence 1191 from Patent EP1572962.
MA619670 - JP 2018138019-A/191596: Polycomb-Associated Non-Coding RNAs.
MA448604 - JP 2018138019-A/20530: Polycomb-Associated Non-Coding RNAs.
MA597322 - JP 2018138019-A/169248: Polycomb-Associated Non-Coding RNAs.

-  Other Names for This Gene
  Alternate Gene Symbols: C7orf39, NM_080660, NP_542391, Q8WUD9, Q96H79, ZCCHL_HUMAN
UCSC ID: uc003vum.1
RefSeq Accession: NM_080660
Protein: Q96H79 (aka ZCCHL_HUMAN)
CCDS: CCDS5850.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_080660.3
exon count: 5CDS single in 3' UTR: no RNA size: 1802
ORF size: 903CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2006.00frame shift in genome: no % Coverage: 97.28
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.