Human Gene TRBV10-2 (uc003vyj.2)
  Description: SubName: Full=V_segment translation product; Flags: Fragment;
Transcript (Including UTRs)
   Position: hg19 chr7:142,206,514-142,207,007 Size: 494 Total Exon Count: 2 Strand: -
Coding Region
   Position: hg19 chr7:142,206,516-142,206,960 Size: 445 Coding Exon Count: 2 

Page IndexSequence and LinksPrimersGene AllelesRNA-Seq ExpressionMicroarray Expression
RNA StructureProtein StructureOther SpeciesmRNA DescriptionsOther NamesModel Information
Methods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr7:142,206,514-142,207,007)mRNA (may differ from genome)Protein (113 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldEnsembl
ExonPrimerGeneCardsHGNCMGIPubMedUniProtKB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
  Highest median expression: 0.21 RPKM in Whole Blood
Total median expression: 0.70 RPKM



View in GTEx track of Genome Browser    View at GTEx portal     View GTEx Body Map

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -19.7047-0.419 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR007110 - Ig-like
IPR013783 - Ig-like_fold
IPR013106 - Ig_V-set

Pfam Domains:
PF07686 - Immunoglobulin V-set domain

SCOP Domains:
48726 - Immunoglobulin

ModBase Predicted Comparative 3D Structure on A0A583
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
Gene Details     
Gene Sorter     
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AB977901 - Homo sapiens mRNA for T cell receptor beta chain V-D-J-region, partial cds, isolate: N(3)-TRB29.
AB977798 - Homo sapiens mRNA for T cell receptor beta chain V-D-J-region, partial cds, isolate: CM(2)-TRB150.
AB977655 - Homo sapiens mRNA for T cell receptor beta chain V-D-J-region, partial cds, isolate: LEM(1)-TRB18.
AB306220 - Homo sapiens mRNA for T cell receptor beta variable 10, partial cds, clone: un 187.
MG790209 - Homo sapiens isolate Sample2_Cell215_4D2_CDR3b T-cell receptor beta chain mRNA, partial sequence.
MG192940 - Homo sapiens isolate HD19_NN14_F4 T cell receptor beta mRNA, partial cds.
MG193060 - Homo sapiens isolate HD20_NN18_E8 T cell receptor beta mRNA, partial cds.
MG193076 - Homo sapiens isolate HD20_NN16_A2 T cell receptor beta mRNA, partial cds.
MG193082 - Homo sapiens isolate HD20_NN17_B6 T cell receptor beta mRNA, partial cds.
KX075904 - Homo sapiens isolate SG_Subject2 clone 131-2 T-cell receptor beta chain variable region (TRB) mRNA, partial cds.
KM004557 - Homo sapiens clone 532 T cell receptor beta mRNA, partial cds.
KM004583 - Homo sapiens clone 558 T cell receptor beta mRNA, partial cds.
MG790590 - Homo sapiens isolate Sample3_Cell140_2E1_CDR3b T-cell receptor beta chain mRNA, partial sequence.
MG789004 - Homo sapiens isolate Sample1_Cell5_11A6_CDR3b T-cell receptor beta chain mRNA, partial sequence.
MG791492 - Homo sapiens isolate AA_Cell224_5D7_CDR3b T-cell receptor beta chain mRNA, partial sequence.
MG791683 - Homo sapiens isolate AA_Cell315_6D9_CDR3b T-cell receptor beta chain mRNA, partial sequence.
AB306250 - Homo sapiens mRNA for T cell receptor beta variable 10, partial cds, clone: un 253.
AB305808 - Homo sapiens mRNA for T cell receptor beta variable 10, partial cds, clone: SEB 26.
AB305991 - Homo sapiens mRNA for T cell receptor beta variable 10, partial cds, clone: SEB 411.
AB977788 - Homo sapiens mRNA for T cell receptor beta chain V-D-J-region, partial cds, isolate: CM(2)-TRB111.
HM236597 - Homo sapiens isolate s124-13_c02_H267_MBP TCR (CDR3) mRNA, partial cds.
KX074288 - Homo sapiens isolate PB_Subject1 clone 67-1 T-cell receptor beta chain variable region (TRB) mRNA, partial cds.
KX075791 - Homo sapiens isolate SG_Subject1 clone 18-1 T-cell receptor beta chain variable region (TRB) mRNA, partial cds.
KX074233 - Homo sapiens isolate PB_Subject1 clone 12-1 T-cell receptor beta chain variable region (TRB) mRNA, partial cds.
KX075832 - Homo sapiens isolate SG_Subject1 clone 59-1 T-cell receptor beta chain variable region (TRB) mRNA, partial cds.
MG192613 - Homo sapiens isolate ACL_NN12_D5 T cell receptor beta mRNA, partial cds.
MG789407 - Homo sapiens isolate Sample1_Cell182_13A11_CDR3b T-cell receptor beta chain mRNA, partial sequence.
MG791609 - Homo sapiens isolate AA_Cell278_6A6_CDR3b T-cell receptor beta chain mRNA, partial sequence.
AB305854 - Homo sapiens mRNA for T cell receptor beta variable 10, partial cds, clone: SEB 131.
U50073 - Human T cell receptor beta chain precursor (Vbeta 12.3) mRNA, complete cds.
AY751307 - Homo sapiens clone RW38 T cell receptor beta chain mRNA, partial cds.
MG789637 - Homo sapiens isolate Sample1_Cell285_18G7_CDR3b T-cell receptor beta chain mRNA, partial sequence.
MG789803 - Homo sapiens isolate Sample2_Cell29_1C5_CDR3b T-cell receptor beta chain mRNA, partial sequence.
X57609 - H.sapiens rearranged TCR Vbeta 12.3 mRNA for T cell receptor.
AB306203 - Homo sapiens mRNA for T cell receptor beta variable 10, partial cds, clone: un 163.
KX075303 - Homo sapiens isolate PB_Subject9 clone 1082-9 T-cell receptor beta chain variable region (TRB) mRNA, partial cds.
KM004604 - Homo sapiens clone 579 T cell receptor beta mRNA, partial cds.
MG193003 - Homo sapiens isolate HD19_NN15_B2 T cell receptor beta mRNA, partial cds.
MG791050 - Homo sapiens isolate AA_Cell21_3B9_CDR3b T-cell receptor beta chain mRNA, partial sequence.
L43588 - Homo sapiens T cell antigen receptor mRNA, partial cds.
AF327020 - Homo sapiens clone 359.11 T cell receptor beta chain mRNA, partial cds.
MG790316 - Homo sapiens isolate Sample3_Cell15_1B3_CDR3b T-cell receptor beta chain mRNA, partial sequence.
S57596 - T-cell-receptor V beta 12.6 [human, mRNA Partial, 63 nt].
KX076579 - Homo sapiens isolate SG_Subject3 clone 806-3 T-cell receptor beta chain variable region (TRB) mRNA, partial cds.
MG193044 - Homo sapiens isolate HD20_NN18_H5 T cell receptor beta mRNA, partial cds.
MG790416 - Homo sapiens isolate Sample3_Cell62_1F4_CDR3b T-cell receptor beta chain mRNA, partial sequence.
AB977502 - Homo sapiens mRNA for T cell receptor beta chain V-D-J-region, partial cds, isolate: N(1)-TRB20.
AB978259 - Homo sapiens mRNA for T cell receptor beta chain V-D-J-region, partial cds, isolate: Donor4-TRB223.
KM004813 - Homo sapiens clone 789 T cell receptor beta mRNA, partial cds.
AB305922 - Homo sapiens mRNA for T cell receptor beta variable 10, partial cds, clone: SEB 295.
AB306184 - Homo sapiens mRNA for T cell receptor beta variable 10, partial cds, clone: un 117.
AB306155 - Homo sapiens mRNA for T cell receptor beta variable 10, partial cds, clone: un 69.
MK088562 - Homo sapiens clone A5030 T cell receptor beta chain (TRB) mRNA, TRB-V10-2*01 allele, partial cds.
LR800336 - Homo Sapiens mRNA for T-cell receptor beta chain (TRB gene), clone WT1 Donor G TRBV10-2*01.
LR800337 - Homo Sapiens mRNA for T-cell receptor beta chain (TRB gene), clone WT1 Donor G TRBV10-2*01.
LR800338 - Homo Sapiens mRNA for T-cell receptor beta chain (TRB gene), clone WT1 Donor G TRBV10-2*01.

-  Other Names for This Gene
  Alternate Gene Symbols: A0A583, A0A583_HUMAN, AB306184, TCRBV12S3
UCSC ID: uc003vyj.2
Representative RNA: AB306184
Protein: A0A583

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: AB306184.1
exon count: 2CDS single in 3' UTR: no RNA size: 335
ORF size: 339CDS single in intron: no Alignment % ID: 99.39
txCdsPredict score: 828.00frame shift in genome: no % Coverage: 97.91
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: no retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.