The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF13402 - Peptidase M60, enhancin and enhancin-like PF17291 - N-terminal domain of M60-like peptidases
ModBase Predicted Comparative 3D Structure on A6NFQ2
Front
Top
Side
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Molecular Function: GO:0044325 ion channel binding
Biological Process: GO:0010360 negative regulation of anion channel activity GO:0030335 positive regulation of cell migration GO:0090314 positive regulation of protein targeting to membrane
AK098041 - Homo sapiens cDNA FLJ40722 fis, clone THYMU2028629. AL832734 - Homo sapiens mRNA; cDNA DKFZp686F2013 (from clone DKFZp686F2013). BC113530 - Homo sapiens family with sequence similarity 115, member C, mRNA (cDNA clone MGC:142090 IMAGE:8322582), complete cds. BC117233 - Homo sapiens family with sequence similarity 115, member C, mRNA (cDNA clone MGC:150842 IMAGE:40125784), complete cds. AY167570 - Homo sapiens unknown mRNA. HQ258592 - Synthetic construct Homo sapiens clone IMAGE:100073128 family with sequence similarity 115, member C (FAM115C), transcript variant 1 (FAM115C) gene, encodes complete protein. HQ258634 - Synthetic construct Homo sapiens clone IMAGE:100073190 family with sequence similarity 115, member C (FAM115C), transcript variant 1 (FAM115C) gene, encodes complete protein. EU832016 - Synthetic construct Homo sapiens clone HAIB:100067045; DKFZo004B1024 family with sequence similarity 139, member A protein (FAM139A) gene, encodes complete protein. EU831922 - Synthetic construct Homo sapiens clone HAIB:100066951; DKFZo008B1023 family with sequence similarity 139, member A protein (FAM139A) gene, encodes complete protein. KJ906482 - Synthetic construct Homo sapiens clone ccsbBroadEn_16152 FAM115C gene, encodes complete protein. AK296318 - Homo sapiens cDNA FLJ57809 complete cds. AK090395 - Homo sapiens mRNA for FLJ00264 protein.