Description: Homo sapiens transforming, acidic coiled-coil containing protein 1 (TACC1), transcript variant 3, mRNA. RefSeq Summary (NM_001146216): This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]. Transcript (Including UTRs) Position: hg19 chr8:38,585,704-38,710,546 Size: 124,843 Total Exon Count: 13 Strand: + Coding Region Position: hg19 chr8:38,677,348-38,705,541 Size: 28,194 Coding Exon Count: 11
ID:E7ET87_HUMAN DESCRIPTION: SubName: Full=Transforming acidic coiled-coil-containing protein 1; CAUTION: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Pfam Domains: PF05010 - Transforming acidic coiled-coil-containing protein (TACC)
ModBase Predicted Comparative 3D Structure on E7ET87
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Descriptions from all associated GenBank mRNAs
BX647696 - Homo sapiens mRNA; cDNA DKFZp686K18126 (from clone DKFZp686K18126). AY072873 - Homo sapiens transforming, acidic coiled-coil containing protein 1 variant TACC1-B (TACC1) mRNA, partial cds; alternatively spliced. AY072876 - Homo sapiens transforming, acidic coiled-coil containing protein 1 variant TACC1-E (TACC1) mRNA, partial cds; alternatively spliced. AK304774 - Homo sapiens cDNA FLJ52058 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. AK295071 - Homo sapiens cDNA FLJ50409 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. AK303596 - Homo sapiens cDNA FLJ52382 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. AK304507 - Homo sapiens cDNA FLJ56209 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. BC041391 - Homo sapiens transforming, acidic coiled-coil containing protein 1, mRNA (cDNA clone MGC:43967 IMAGE:5276767), complete cds. JF432777 - Synthetic construct Homo sapiens clone IMAGE:100074021 transforming, acidic coiled-coil containing protein 1 (TACC1) gene, encodes complete protein. KJ901774 - Synthetic construct Homo sapiens clone ccsbBroadEn_11168 TACC1 gene, encodes complete protein. AY072874 - Homo sapiens transforming, acidic coiled-coil containing protein 1 variant TACC1-C (TACC1) mRNA, partial cds; alternatively spliced. AY072875 - Homo sapiens transforming, acidic coiled-coil containing protein 1 variant TACC1-D (TACC1) mRNA, partial cds; alternatively spliced. AK308849 - Homo sapiens cDNA, FLJ98890. AK314620 - Homo sapiens cDNA, FLJ95461, highly similar to Homo sapiens transforming, acidic coiled-coil containing protein 1 (TACC1), mRNA. AF049910 - Homo sapiens TACC1 (TACC1) mRNA, complete cds. AY177411 - Homo sapiens transforming acidic coiled-coil containing protein 1 short isoform (TACC1) mRNA, complete cds. AB463317 - Synthetic construct DNA, clone: pF1KB9572, Homo sapiens TACC1 gene for transforming, acidic coiled-coil containing protein 1, without stop codon, in Flexi system. AK294931 - Homo sapiens cDNA FLJ50512 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. AK295841 - Homo sapiens cDNA FLJ50411 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. AK124297 - Homo sapiens cDNA FLJ42304 fis, clone TRACH2001403. AB029026 - Homo sapiens mRNA for KIAA1103 protein, partial cds. AK304725 - Homo sapiens cDNA FLJ52297 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. AY039239 - Homo sapiens gastric cancer antigen Ga55 (TACC1) mRNA, partial cds. AY139007 - Homo sapiens TACC1-like protein mRNA, complete cds. AK098223 - Homo sapiens cDNA FLJ40904 fis, clone UTERU2004564. JD269219 - Sequence 250243 from Patent EP1572962. JD518997 - Sequence 500021 from Patent EP1572962. JD232862 - Sequence 213886 from Patent EP1572962. JD460356 - Sequence 441380 from Patent EP1572962. JD562431 - Sequence 543455 from Patent EP1572962. JD090700 - Sequence 71724 from Patent EP1572962. JD432693 - Sequence 413717 from Patent EP1572962. JD097217 - Sequence 78241 from Patent EP1572962. JD366946 - Sequence 347970 from Patent EP1572962. JD488925 - Sequence 469949 from Patent EP1572962. JD215340 - Sequence 196364 from Patent EP1572962. JD066446 - Sequence 47470 from Patent EP1572962. JD299305 - Sequence 280329 from Patent EP1572962. JD111988 - Sequence 93012 from Patent EP1572962. JD498058 - Sequence 479082 from Patent EP1572962. JD564664 - Sequence 545688 from Patent EP1572962. JD416178 - Sequence 397202 from Patent EP1572962. JD082630 - Sequence 63654 from Patent EP1572962. JD061437 - Sequence 42461 from Patent EP1572962. JD451221 - Sequence 432245 from Patent EP1572962. JD376142 - Sequence 357166 from Patent EP1572962. JD376143 - Sequence 357167 from Patent EP1572962. JD498039 - Sequence 479063 from Patent EP1572962. JD276461 - Sequence 257485 from Patent EP1572962. JD553521 - Sequence 534545 from Patent EP1572962. JD431286 - Sequence 412310 from Patent EP1572962. JD564036 - Sequence 545060 from Patent EP1572962. JD557159 - Sequence 538183 from Patent EP1572962. JD088620 - Sequence 69644 from Patent EP1572962. JD267398 - Sequence 248422 from Patent EP1572962. JD447678 - Sequence 428702 from Patent EP1572962. JD085109 - Sequence 66133 from Patent EP1572962. JD249564 - Sequence 230588 from Patent EP1572962. JD378010 - Sequence 359034 from Patent EP1572962. JD354049 - Sequence 335073 from Patent EP1572962. JD269657 - Sequence 250681 from Patent EP1572962. JD189797 - Sequence 170821 from Patent EP1572962. JD251491 - Sequence 232515 from Patent EP1572962. JD036424 - Sequence 17448 from Patent EP1572962. JD036748 - Sequence 17772 from Patent EP1572962. JD433674 - Sequence 414698 from Patent EP1572962. JD234837 - Sequence 215861 from Patent EP1572962. JD483720 - Sequence 464744 from Patent EP1572962. JD048828 - Sequence 29852 from Patent EP1572962. JD369324 - Sequence 350348 from Patent EP1572962. JD300223 - Sequence 281247 from Patent EP1572962. JD314705 - Sequence 295729 from Patent EP1572962. DQ601424 - Homo sapiens piRNA piR-39490, complete sequence. JD170964 - Sequence 151988 from Patent EP1572962. JD554021 - Sequence 535045 from Patent EP1572962. JD516773 - Sequence 497797 from Patent EP1572962. JD313559 - Sequence 294583 from Patent EP1572962. JD343373 - Sequence 324397 from Patent EP1572962. JD378971 - Sequence 359995 from Patent EP1572962. JD389673 - Sequence 370697 from Patent EP1572962. JD292900 - Sequence 273924 from Patent EP1572962. JD061641 - Sequence 42665 from Patent EP1572962. JD466145 - Sequence 447169 from Patent EP1572962. JD281080 - Sequence 262104 from Patent EP1572962. JD209510 - Sequence 190534 from Patent EP1572962. JD333433 - Sequence 314457 from Patent EP1572962. JD182987 - Sequence 164011 from Patent EP1572962. JD093916 - Sequence 74940 from Patent EP1572962. AF075051 - Homo sapiens full length insert cDNA YN99C01. JD355069 - Sequence 336093 from Patent EP1572962. JD552697 - Sequence 533721 from Patent EP1572962. JD363699 - Sequence 344723 from Patent EP1572962. JD368311 - Sequence 349335 from Patent EP1572962.