Description: Homo sapiens transforming, acidic coiled-coil containing protein 1 (TACC1), transcript variant 2, mRNA. RefSeq Summary (NM_001122824): This locus may represent a breast cancer candidate gene. It is located close to FGFR1 on a region of chromosome 8 that is amplified in some breast cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2017]. Transcript (Including UTRs) Position: hg19 chr8:38,614,757-38,688,695 Size: 73,939 Total Exon Count: 5 Strand: + Coding Region Position: hg19 chr8:38,614,851-38,688,695 Size: 73,845 Coding Exon Count: 5
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse
Rat
Zebrafish
D. melanogaster
C. elegans
S. cerevisiae
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
No ortholog
Descriptions from all associated GenBank mRNAs
BX647696 - Homo sapiens mRNA; cDNA DKFZp686K18126 (from clone DKFZp686K18126). AY072873 - Homo sapiens transforming, acidic coiled-coil containing protein 1 variant TACC1-B (TACC1) mRNA, partial cds; alternatively spliced. AY072876 - Homo sapiens transforming, acidic coiled-coil containing protein 1 variant TACC1-E (TACC1) mRNA, partial cds; alternatively spliced. AK304774 - Homo sapiens cDNA FLJ52058 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. AK295071 - Homo sapiens cDNA FLJ50409 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. AK303596 - Homo sapiens cDNA FLJ52382 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. AK304507 - Homo sapiens cDNA FLJ56209 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. BC041391 - Homo sapiens transforming, acidic coiled-coil containing protein 1, mRNA (cDNA clone MGC:43967 IMAGE:5276767), complete cds. JF432777 - Synthetic construct Homo sapiens clone IMAGE:100074021 transforming, acidic coiled-coil containing protein 1 (TACC1) gene, encodes complete protein. KJ901774 - Synthetic construct Homo sapiens clone ccsbBroadEn_11168 TACC1 gene, encodes complete protein. AY072874 - Homo sapiens transforming, acidic coiled-coil containing protein 1 variant TACC1-C (TACC1) mRNA, partial cds; alternatively spliced. AY072875 - Homo sapiens transforming, acidic coiled-coil containing protein 1 variant TACC1-D (TACC1) mRNA, partial cds; alternatively spliced. AK308849 - Homo sapiens cDNA, FLJ98890. AK314620 - Homo sapiens cDNA, FLJ95461, highly similar to Homo sapiens transforming, acidic coiled-coil containing protein 1 (TACC1), mRNA. AF049910 - Homo sapiens TACC1 (TACC1) mRNA, complete cds. AY177411 - Homo sapiens transforming acidic coiled-coil containing protein 1 short isoform (TACC1) mRNA, complete cds. AB463317 - Synthetic construct DNA, clone: pF1KB9572, Homo sapiens TACC1 gene for transforming, acidic coiled-coil containing protein 1, without stop codon, in Flexi system. AK294931 - Homo sapiens cDNA FLJ50512 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. AK295841 - Homo sapiens cDNA FLJ50411 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. AB029026 - Homo sapiens mRNA for KIAA1103 protein, partial cds. AK304725 - Homo sapiens cDNA FLJ52297 complete cds, highly similar to Transforming acidic coiled-coil-containing protein 1. AY039239 - Homo sapiens gastric cancer antigen Ga55 (TACC1) mRNA, partial cds.