Human Gene DOCK8-AS1 (uc003zge.4)
  Description: Homo sapiens chromosome 9 open reading frame 66 (DOCK8-AS1), mRNA.
Transcript (Including UTRs)
   Position: hg19 chr9:213,108-215,893 Size: 2,786 Total Exon Count: 1 Strand: -
Coding Region
   Position: hg19 chr9:214,509-215,396 Size: 888 Coding Exon Count: 1 

Page IndexSequence and LinksPrimersGene AllelesRNA StructureProtein Structure
Other SpeciesmRNA DescriptionsOther NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr9:213,108-215,893)mRNA (may differ from genome)Protein (295 aa)
Gene SorterGenome BrowserOther Species FASTATable SchemaAlphaFoldBioGPS
EnsemblExonPrimerGeneCardsGeneNetworkHPRDLynx
MGIneXtProtPubMedUniProtKB

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -133.90497-0.269 Picture PostScript Text
3' UTR -424.201401-0.303 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  ModBase Predicted Comparative 3D Structure on Q5T8R8
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Descriptions from all associated GenBank mRNAs
  AK055720 - Homo sapiens cDNA FLJ31158 fis, clone KIDNE1000008.
JD060346 - Sequence 41370 from Patent EP1572962.
JD497633 - Sequence 478657 from Patent EP1572962.
JD194262 - Sequence 175286 from Patent EP1572962.
JD149294 - Sequence 130318 from Patent EP1572962.
JD332561 - Sequence 313585 from Patent EP1572962.
JD176014 - Sequence 157038 from Patent EP1572962.
JD073052 - Sequence 54076 from Patent EP1572962.
JD444767 - Sequence 425791 from Patent EP1572962.
JD452302 - Sequence 433326 from Patent EP1572962.
JD139906 - Sequence 120930 from Patent EP1572962.
JD076503 - Sequence 57527 from Patent EP1572962.
JD349711 - Sequence 330735 from Patent EP1572962.
JD297187 - Sequence 278211 from Patent EP1572962.
BC111423 - Homo sapiens chromosome 9 open reading frame 66, mRNA (cDNA clone IMAGE:40032021), complete cds.
JD046899 - Sequence 27923 from Patent EP1572962.
JD533968 - Sequence 514992 from Patent EP1572962.
JD408019 - Sequence 389043 from Patent EP1572962.
JD526491 - Sequence 507515 from Patent EP1572962.
JD048085 - Sequence 29109 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: C9orf66, CI066_HUMAN, NM_152569, NP_689782, Q5T8R8, Q96NB0
UCSC ID: uc003zge.4
RefSeq Accession: NM_152569
Protein: Q5T8R8 (aka CI066_HUMAN)
CCDS: CCDS6439.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_152569.2
exon count: 1CDS single in 3' UTR: no RNA size: 2786
ORF size: 888CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1262.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.