Human Gene ZBTB6 (uc004bnh.4)
Description: Homo sapiens zinc finger and BTB domain containing 6 (ZBTB6), mRNA.
Transcript (Including UTRs)
Position: hg19 chr9:125,670,335-125,675,607 Size: 5,273 Total Exon Count: 2 Strand: -
Coding Region
Position: hg19 chr9:125,673,077-125,674,351 Size: 1,275 Coding Exon Count: 1
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: ZBTB6_HUMAN
DESCRIPTION: RecName: Full=Zinc finger and BTB domain-containing protein 6; AltName: Full=Zinc finger protein 482; AltName: Full=Zinc finger protein with interaction domain;
FUNCTION: May be involved in transcriptional regulation.SUBCELLULAR LOCATION: Nucleus.TISSUE SPECIFICITY: Widely expressed with highest levels in brain.SIMILARITY: Contains 1 BTB (POZ) domain.SIMILARITY: Contains 4 C2H2-type zinc fingers.
Primer design for this transcript
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR000210 - BTB/POZ-like
IPR011333 - BTB/POZ_fold
IPR013069 - BTB_POZ
IPR007087 - Znf_C2H2
IPR015880 - Znf_C2H2-like
IPR013087 - Znf_C2H2/integrase_DNA-bd
Pfam Domains: PF00096 - Zinc finger, C2H2 type
PF00651 - BTB/POZ domain
PF12874 - Zinc-finger of C2H2 type
PF13894 - C2H2-type zinc finger
SCOP Domains: 54695 - POZ domain
57667 - C2H2 and C2HC zinc fingers
ModBase Predicted Comparative 3D Structure on Q15916
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
LF205680 - JP 2014500723-A/13183: Polycomb-Associated Non-Coding RNAs.BC037282 - Homo sapiens zinc finger and BTB domain containing 6, mRNA (cDNA clone MGC:33077 IMAGE:5266759), complete cds.AK098650 - Homo sapiens cDNA FLJ25784 fis, clone TST06730.JD087823 - Sequence 68847 from Patent EP1572962.LF347068 - JP 2014500723-A/154571: Polycomb-Associated Non-Coding RNAs.JD555393 - Sequence 536417 from Patent EP1572962.JD053168 - Sequence 34192 from Patent EP1572962.LF347069 - JP 2014500723-A/154572: Polycomb-Associated Non-Coding RNAs.X82018 - H.sapiens mRNA for ZID protein.JD062299 - Sequence 43323 from Patent EP1572962.JD438710 - Sequence 419734 from Patent EP1572962.JD043071 - Sequence 24095 from Patent EP1572962.JD500657 - Sequence 481681 from Patent EP1572962.JD502579 - Sequence 483603 from Patent EP1572962.JD511069 - Sequence 492093 from Patent EP1572962.JD088036 - Sequence 69060 from Patent EP1572962.JD299781 - Sequence 280805 from Patent EP1572962.JD566247 - Sequence 547271 from Patent EP1572962.JD497236 - Sequence 478260 from Patent EP1572962.JD036377 - Sequence 17401 from Patent EP1572962.AK292401 - Homo sapiens cDNA FLJ77379 complete cds, highly similar to Homo sapiens zinc finger protein 482 (ZNF482), mRNA.JD240221 - Sequence 221245 from Patent EP1572962.JD310839 - Sequence 291863 from Patent EP1572962.JD262817 - Sequence 243841 from Patent EP1572962.JD256905 - Sequence 237929 from Patent EP1572962.JD507392 - Sequence 488416 from Patent EP1572962.JD450402 - Sequence 431426 from Patent EP1572962.LF347070 - JP 2014500723-A/154573: Polycomb-Associated Non-Coding RNAs.KJ893131 - Synthetic construct Homo sapiens clone ccsbBroadEn_02525 ZBTB6 gene, encodes complete protein.EU446768 - Synthetic construct Homo sapiens clone IMAGE:100070262; IMAGE:100011977; FLH258218.01L zinc finger and BTB domain containing 6 (ZBTB6) gene, encodes complete protein.AB464748 - Synthetic construct DNA, clone: pF1KB9672, Homo sapiens ZBTB6 gene for zinc finger and BTB domain containing protein 6, without stop codon, in Flexi system.LF347071 - JP 2014500723-A/154574: Polycomb-Associated Non-Coding RNAs.LF347072 - JP 2014500723-A/154575: Polycomb-Associated Non-Coding RNAs.LF347073 - JP 2014500723-A/154576: Polycomb-Associated Non-Coding RNAs.LF347074 - JP 2014500723-A/154577: Polycomb-Associated Non-Coding RNAs.LF347078 - JP 2014500723-A/154581: Polycomb-Associated Non-Coding RNAs.MA582645 - JP 2018138019-A/154571: Polycomb-Associated Non-Coding RNAs.MA582646 - JP 2018138019-A/154572: Polycomb-Associated Non-Coding RNAs.MA582647 - JP 2018138019-A/154573: Polycomb-Associated Non-Coding RNAs.MA582648 - JP 2018138019-A/154574: Polycomb-Associated Non-Coding RNAs.MA582649 - JP 2018138019-A/154575: Polycomb-Associated Non-Coding RNAs.MA582650 - JP 2018138019-A/154576: Polycomb-Associated Non-Coding RNAs.MA582651 - JP 2018138019-A/154577: Polycomb-Associated Non-Coding RNAs.MA582655 - JP 2018138019-A/154581: Polycomb-Associated Non-Coding RNAs.MA441257 - JP 2018138019-A/13183: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: A8K8N6, NM_006626, NP_006617, Q15916, uc004bnh.3, ZBTB6_HUMAN, ZID, ZNF482UCSC ID: uc004bnh.4RefSeq Accession: NM_006626
Protein: Q15916
(aka ZBTB6_HUMAN)
CCDS: CCDS6846.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_006626.5
exon count:
2 CDS single in 3' UTR:
no
RNA size:
4111
ORF size:
1275 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
2750.00 frame shift in genome:
no
% Coverage:
99.83
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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