Human Gene TOR4A (uc004cmn.3)
Description: Homo sapiens torsin family 4, member A (TOR4A), mRNA.
Transcript (Including UTRs)
Position: hg19 chr9:140,172,280-140,177,093 Size: 4,814 Total Exon Count: 2 Strand: +
Coding Region
Position: hg19 chr9:140,173,142-140,174,413 Size: 1,272 Coding Exon Count: 1
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Comments and Description Text from UniProtKB
ID: TOR4A_HUMAN
DESCRIPTION: RecName: Full=Torsin-4A; AltName: Full=Torsin family 4 member A;
SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein (Potential).SIMILARITY: Belongs to the clpA/clpB family. Torsin subfamily.
Primer design for this transcript
Comparative Toxicogenomics Database (CTD)
The following chemicals interact with this gene
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR003593 - AAA+_ATPase
IPR010448 - Torsin
Pfam Domains: PF06309 - Torsin
SCOP Domains: 52540 - P-loop containing nucleoside triphosphate hydrolases
ModBase Predicted Comparative 3D Structure on Q9NXH8
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Mouse Rat Zebrafish D. melanogaster C. elegans S. cerevisiae
No ortholog No ortholog No ortholog No ortholog No ortholog No ortholog
Gene Details
Gene Sorter
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
LF205575 - JP 2014500723-A/13078: Polycomb-Associated Non-Coding RNAs.JD274377 - Sequence 255401 from Patent EP1572962.AK000252 - Homo sapiens cDNA FLJ20245 fis, clone COLF6454.BC169268 - Synthetic construct Homo sapiens clone IMAGE:9093398 hypothetical protein LOC54863 (C9orf167) gene, partial cds.BC169269 - Synthetic construct Homo sapiens clone IMAGE:9093399 hypothetical protein LOC54863 (C9orf167) gene, partial cds.BC169270 - Synthetic construct Homo sapiens clone IMAGE:9093400 hypothetical protein LOC54863 (C9orf167) gene, partial cds.AK000392 - Homo sapiens cDNA FLJ20385 fis, clone KAIA4085.BC169271 - Synthetic construct Homo sapiens clone IMAGE:9093396 hypothetical protein LOC54863 (C9orf167) gene, partial cds.JD323639 - Sequence 304663 from Patent EP1572962.JD278554 - Sequence 259578 from Patent EP1572962.JD078609 - Sequence 59633 from Patent EP1572962.JD493207 - Sequence 474231 from Patent EP1572962.JD334429 - Sequence 315453 from Patent EP1572962.JD106986 - Sequence 88010 from Patent EP1572962.JD527297 - Sequence 508321 from Patent EP1572962.AK023361 - Homo sapiens cDNA FLJ13299 fis, clone OVARC1001339.JD559211 - Sequence 540235 from Patent EP1572962.JD544171 - Sequence 525195 from Patent EP1572962.JD115897 - Sequence 96921 from Patent EP1572962.JD227961 - Sequence 208985 from Patent EP1572962.JD288004 - Sequence 269028 from Patent EP1572962.JD514858 - Sequence 495882 from Patent EP1572962.JD318662 - Sequence 299686 from Patent EP1572962.JD141717 - Sequence 122741 from Patent EP1572962.JD515072 - Sequence 496096 from Patent EP1572962.JD146184 - Sequence 127208 from Patent EP1572962.JD477127 - Sequence 458151 from Patent EP1572962.JD318769 - Sequence 299793 from Patent EP1572962.JD127012 - Sequence 108036 from Patent EP1572962.JD558993 - Sequence 540017 from Patent EP1572962.JD335820 - Sequence 316844 from Patent EP1572962.JD523219 - Sequence 504243 from Patent EP1572962.JD485463 - Sequence 466487 from Patent EP1572962.JD406560 - Sequence 387584 from Patent EP1572962.JD234815 - Sequence 215839 from Patent EP1572962.JD464981 - Sequence 446005 from Patent EP1572962.JD227192 - Sequence 208216 from Patent EP1572962.JD416400 - Sequence 397424 from Patent EP1572962.JD394408 - Sequence 375432 from Patent EP1572962.JD196977 - Sequence 178001 from Patent EP1572962.JD040982 - Sequence 22006 from Patent EP1572962.JD384238 - Sequence 365262 from Patent EP1572962.JD214633 - Sequence 195657 from Patent EP1572962.JD204513 - Sequence 185537 from Patent EP1572962.JD460908 - Sequence 441932 from Patent EP1572962.JD345977 - Sequence 327001 from Patent EP1572962.JD213581 - Sequence 194605 from Patent EP1572962.JD233793 - Sequence 214817 from Patent EP1572962.JD207630 - Sequence 188654 from Patent EP1572962.JD341503 - Sequence 322527 from Patent EP1572962.JD212098 - Sequence 193122 from Patent EP1572962.MA441152 - JP 2018138019-A/13078: Polycomb-Associated Non-Coding RNAs.
Biochemical and Signaling Pathways
Other Names for This Gene
Alternate Gene Symbols: A2BFA4, C9orf167, NM_017723, NP_060193, Q9NXH8, TOR4A_HUMANUCSC ID: uc004cmn.3RefSeq Accession: NM_017723
Protein: Q9NXH8
(aka TOR4A_HUMAN)
CCDS: CCDS7041.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_017723.2
exon count:
2 CDS single in 3' UTR:
no
RNA size:
4069
ORF size:
1272 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
2732.50 frame shift in genome:
no
% Coverage:
100.00
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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for details on how this gene model was made and data restrictions if any.