Human Gene SRPX (uc004ddz.2)
Description: Homo sapiens sushi-repeat containing protein, X-linked (SRPX), transcript variant 2, mRNA.
Transcript (Including UTRs)
Position: hg19 chrX:38,008,588-38,080,177 Size: 71,590 Total Exon Count: 9 Strand: -
Coding Region
Position: hg19 chrX:38,008,964-38,080,045 Size: 71,082 Coding Exon Count: 9
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
Press "+" in the title bar above to open this section.
RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
Press "+" in the title bar above to open this section.
mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR016060 - Complement_control_module
IPR025232 - DUF4174
IPR003410 - Hyalin
IPR000436 - Sushi_SCR_CCP
Pfam Domains: PF00084 - Sushi repeat (SCR repeat)
PF02494 - HYR domain
PF13778 - Domain of unknown function (DUF4174)
SCOP Domains: 57535 - Complement control module/SCR domain
ModBase Predicted Comparative 3D Structure on G3V1L0
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Descriptions from all associated GenBank mRNAs
LF214065 - JP 2014500723-A/21568: Polycomb-Associated Non-Coding RNAs.LF211414 - JP 2014500723-A/18917: Polycomb-Associated Non-Coding RNAs.BC020684 - Homo sapiens sushi-repeat-containing protein, X-linked, mRNA (cDNA clone MGC:22406 IMAGE:4731946), complete cds.AK125542 - Homo sapiens cDNA FLJ43554 fis, clone PROST2018090, highly similar to SUSHI REPEAT-CONTAINING PROTEIN SRPX PRECURSOR.EU668359 - Homo sapiens epididymis secretory sperm binding protein Li 83p (HEL-S-83p) mRNA, complete cds.U61374 - Human novel protein with short consensus repeats of six cysteines mRNA, complete cds.U78093 - Human sushi-repeat-containing protein precursor (SRPX) mRNA, complete cds.AK293127 - Homo sapiens cDNA FLJ56529 complete cds, highly similar to Sushi repeat-containing protein SRPX precursor.AK289430 - Homo sapiens cDNA FLJ76202 complete cds, highly similar to Homo sapiens sushi-repeat-containing protein, X-linked (SRPX), mRNA.AK298802 - Homo sapiens cDNA FLJ57806 complete cds, highly similar to Sushi repeat-containing protein SRPX precursor.KJ892528 - Synthetic construct Homo sapiens clone ccsbBroadEn_01922 SRPX gene, encodes complete protein.AB527644 - Synthetic construct DNA, clone: pF1KB5557, Homo sapiens SRPX gene for sushi-repeat-containing protein, X-linked, without stop codon, in Flexi system.MA449642 - JP 2018138019-A/21568: Polycomb-Associated Non-Coding RNAs.MA446991 - JP 2018138019-A/18917: Polycomb-Associated Non-Coding RNAs.LF379216 - JP 2014500723-A/186719: Polycomb-Associated Non-Coding RNAs.JD289478 - Sequence 270502 from Patent EP1572962.JD439271 - Sequence 420295 from Patent EP1572962.JD087901 - Sequence 68925 from Patent EP1572962.JD473370 - Sequence 454394 from Patent EP1572962.JD048649 - Sequence 29673 from Patent EP1572962.MA614793 - JP 2018138019-A/186719: Polycomb-Associated Non-Coding RNAs.LF379218 - JP 2014500723-A/186721: Polycomb-Associated Non-Coding RNAs.LF379220 - JP 2014500723-A/186723: Polycomb-Associated Non-Coding RNAs.CU676640 - Synthetic construct Homo sapiens gateway clone IMAGE:100022266 5' read SRPX mRNA.MA614795 - JP 2018138019-A/186721: Polycomb-Associated Non-Coding RNAs.MA614797 - JP 2018138019-A/186723: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_001170750.1
exon count:
9 CDS single in 3' UTR:
no
RNA size:
1860
ORF size:
1335 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
2867.00 frame shift in genome:
no
% Coverage:
99.09
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
Click here
for a detailed description of the fields of the table above.
Methods, Credits, and Use Restrictions
Click here
for details on how this gene model was made and data restrictions if any.