Description: Homo sapiens G protein-coupled receptor associated sorting protein 2 (GPRASP2), transcript variant 2, mRNA. RefSeq Summary (NM_138437): The protein encoded by this gene is a member of a family that regulates the activity of G protein-coupled receptors (GPCRs). The encoded protein has been shown to be capable of interacting with several GPCRs, including the M1 muscarinic acetylcholine receptor and the calcitonin receptor. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]. Transcript (Including UTRs) Position: hg19 chrX:101,967,104-101,972,661 Size: 5,558 Total Exon Count: 4 Strand: + Coding Region Position: hg19 chrX:101,969,798-101,972,314 Size: 2,517 Coding Exon Count: 1
ID:GASP2_HUMAN DESCRIPTION: RecName: Full=G-protein coupled receptor-associated sorting protein 2; Short=GASP-2; FUNCTION: May play a role in regulation of a variety of G-protein coupled receptors. SUBUNIT: Interacts with cytoplasmic tails of a variety of G- protein coupled receptors such as muscarinic acetylcholine receptor M1/CHRM1 and calcitonin receptor/CALCR. TISSUE SPECIFICITY: Expressed in the brain. SIMILARITY: Belongs to the GPRASP family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q96D09
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
US Server
