Human Gene TEX13A (uc004ema.3)
  Description: Homo sapiens testis expressed 13A (TEX13A), mRNA.
RefSeq Summary (NM_031274): This gene is similar to a mouse gene that is expressed in the testis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014].
Transcript (Including UTRs)
   Position: hg19 chrX:104,463,611-104,465,358 Size: 1,748 Total Exon Count: 4 Strand: -
Coding Region
   Position: hg19 chrX:104,463,646-104,465,081 Size: 1,436 Coding Exon Count: 3 

Page IndexSequence and LinksUniProtKB CommentsPrimersCTDGene Alleles
Microarray ExpressionRNA StructureProtein StructureOther SpeciesGO AnnotationsmRNA Descriptions
Other NamesModel InformationMethods
Data last updated at UCSC: 2013-06-14

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrX:104,463,611-104,465,358)mRNA (may differ from genome)Protein (409 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAlphaFold
BioGPSEnsemblEntrez GeneExonPrimerGeneCardsGeneNetwork
H-INVHGNCHPRDLynxMGIneXtProt
OMIMPubMedTreefamUniProtKBBioGrid CRISPR DB

-  Comments and Description Text from UniProtKB
  ID: TX13A_HUMAN
DESCRIPTION: RecName: Full=Testis-expressed sequence 13A protein;
TISSUE SPECIFICITY: Testis specific.
SIMILARITY: Contains 1 RanBP2-type zinc finger.
SEQUENCE CAUTION: Sequence=CAI41996.1; Type=Erroneous gene model prediction;

-  Primer design for this transcript
 

Primer3Plus can design qPCR Primers that straddle exon-exon-junctions, which amplify only cDNA, not genomic DNA.
Click here to load the transcript sequence and exon structure into Primer3Plus

Exonprimer can design one pair of Sanger sequencing primers around every exon, located in non-genic sequence.
Click here to open Exonprimer with this transcript

To design primers for a non-coding sequence, zoom to a region of interest and select from the drop-down menu: View > In External Tools > Primer3


-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene

+  Common Gene Haplotype Alleles
  Press "+" in the title bar above to open this section.

+  Microarray Expression Data
  Press "+" in the title bar above to open this section.

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -40.00112-0.357 Picture PostScript Text
3' UTR -5.6035-0.160 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR001876 - Znf_RanBP2

Pfam Domains:
PF00641 - Zn-finger in Ran binding protein and others
PF15186 - Testis-expressed sequence 13 protein family

SCOP Domains:
90209 - Znf265, first zinc-finger domain

ModBase Predicted Comparative 3D Structure on Q9BXU3
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
MouseRatZebrafishD. melanogasterC. elegansS. cerevisiae
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0005515 protein binding
GO:0046872 metal ion binding


-  Descriptions from all associated GenBank mRNAs
  AF285597 - Homo sapiens testis protein TEX13A (TEX13A) mRNA, complete cds.
LP896581 - Sequence 1445 from Patent EP3253886.
BC108734 - Homo sapiens testis expressed 13A, mRNA (cDNA clone MGC:131984 IMAGE:5744723), complete cds.
BC042547 - Homo sapiens testis expressed 13A, mRNA (cDNA clone MGC:34073 IMAGE:5164310), complete cds.
JF432424 - Synthetic construct Homo sapiens clone IMAGE:100073631 testis expressed 13A (TEX13A) gene, encodes complete protein.
KJ894315 - Synthetic construct Homo sapiens clone ccsbBroadEn_03709 TEX13A gene, encodes complete protein.
EU447013 - Synthetic construct Homo sapiens clone IMAGE:100069998; IMAGE:100012222; FLH257177.01L testis expressed 13A (TEX13A) gene, encodes complete protein.
CU692092 - Synthetic construct Homo sapiens gateway clone IMAGE:100021195 5' read TEX13A mRNA.
JD541706 - Sequence 522730 from Patent EP1572962.

-  Other Names for This Gene
  Alternate Gene Symbols: B1B1G8, NM_031274, NP_112564, Q32NB6, Q9BXU3, TX13A_HUMAN
UCSC ID: uc004ema.3
RefSeq Accession: NM_031274
Protein: Q9BXU3 (aka TX13A_HUMAN or TX3A_HUMAN)

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_031274.3
exon count: 4CDS single in 3' UTR: no RNA size: 1390
ORF size: 1232CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 2313.00frame shift in genome: no % Coverage: 98.63
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.